Finding a preventable cause of leukaemia

1 March 2010

This year alone more than 600 Australian children will be diagnosed with cancer. Whilst survival rates for some childhood leukaemias have improved dramatically, from 20 per cent in the 1970's to 80 per cent today, the same number of children are still getting cancer.

The Murdoch Childrens is heading up the world's largest study into the case of leukaemia, the most common cause of preventable childhood cancer.

Led by our Director, Professor Terry Dwyer AO AM MPH, Murdoch Childrens will lead a global team of scientists to track one million pregnant mothers and their babies.

The project spans four continents with research teams from 15 countries including England, China, Japan, United Sates of America, Norway & Denmark.

This project will use the same methods used by Professor Dwyer's team which lead to the discovery in the early 1990's that sleeping babies on their stomachs is the biggest risk factor for Sudden Infant Death Syndrome (SIDS). This discovery and the subsequent public health campaign lead to an 80 per cent decrease in SIDS related deaths in many developed countries.

By taking hundreds of measurements on the mothers and babies taking part in this cancer study we hope to be able to identify environmental and genetic factors that differ between children who get cancer and those who don't. Having data collected from mothers and babies across the globe allows us to examine how potentially important causes of childhood cancer differ across countries.

If successful we hope that we will be able to produce a set of recommendations that can be implemented to reduce the risk of children developing childhood cancer.