Study reveals link between childhood eczema and adult asthma

3 May 2011

Children who have eczema, particularly when occurring with hay fever, are nine times more likely to develop allergic asthma in their 40s, a new study reveals.

The study, which was conducted by the Murdoch Childrens Research Institute, the University of Melbourne, Menzies Research Institute and Monash University and published online in the Journal of Allergy and Clinical Immunology, reported on evidence from a clinical study of around 1400 people and found that up to 30 per cent of allergic asthma within the population sample could be attributed to a history of childhood eczema and hay fever.

The participants were initially assessed about their allergies and childhood environment in 1967, at seven years of age, and were followed up in 2004, at the age of 44.

Lead author Pamela Martin, a University of Melbourne PhD student based at the Murdoch Children Research Institute analysed the survey and skin prick testing data and said the study showed that childhood eczema, particularly when hay fever also occurs, is a very strong predictor of who will suffer from allergic asthma in adult life.

"The implications of this study are that prevention and rigorous treatment of childhood eczema and hay fever may prevent the persistence and development of asthma," she said.

Pamela said this is the first study to distinguish between allergic and non-allergic asthma and their occurrence after childhood eczema and hay fever, as part of a sequence of allergic illnesses dubbed the 'atopic march'.

"If successful strategies to stop the 'atopic march' are identified, this could ultimately save lives and health care costs related to asthma management and treatment," she said.

The researchers estimate that up to 30 per cent of current allergic asthma within the larger population sample could be attributed to a history of childhood eczema and hay fever.