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Haematology Research

The Haematology Research laboratory studies the blood flow system in neonates and children, its interaction with anticoagulation drugs which are now used more commonly to stop bleeding in children, as well as the differences in the blood clotting proteins during development and ageing.

Research overview

Key research areas
:       

  • Developmental haemostasis: age-related differences in the haemostatic system. 
  • Interaction of the haemostatic system with clinically important anticoagulants.
  • Differences in the plasma proteome in infants and children compared to adults.
  • Changes in the plasma proteome during cardiac surgery (collaboration).
  • Investigation of placental coagulation markers in fetal growth restriction (collaboration).

Research aims:

  • To improve understanding and treatment of blood clotting disorders in children.
  • To better understand, use and monitor anticoagulation therapy in children.
  • To understand how age-related changes in the haemostatic system affect our growth and development.
  • To understand how plasma proteome changes with age and the implications of these changes in the development of diseases associated with the process of ageing.

Professor Paul Monagle
Haematology Research
Murdoch Children's Research Institute
Room SW1033, 10th Floor Research Precinct Building 
Royal Children's Hospital
Flemington Road
Parkville Victoria 3052
Australia
T +61 3 9345 5161
E  paul.monagle@rch.org.au