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Research at the Murdoch Childrens Research Institute - M_POWR Obesity Research

Cross-sectional studies (studies examining children at one point in time)

Addressing Type 2 diabetes in the childhood and adolescent population in Australia: Phase I - Identification of children/adolescents with established Type 2 diabetes (2008-2009).

Even though Type 1 and Type 2 diabetes both mean there is a problem in the way a person’s body deals with sugar (insulin), they are quite different diseases with different causes and treatments. Not much is known about Type 2 diabetes in youth because it has, until recently, been a problem that only develops in older adults. However, due to the recent increases in childhood obesity, Type 2 diabetes is now emerging as a significant problem in youth. This project will try to find out how many and which children are developing Type 2 diabetes. This is important for modelling current health-care strategies so that doctors know how many children they will have to treat over the next decade. It is also important for the future so that doctors and hospitals can be ready for the other health problems that can happen to people with Type 2 diabetes. As this problem is relatively new in the childhood and adolescent population, it is important to start looking at ways to prevent this problem occurring in other children as well as stopping the development of other health problems in those with established disease.

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Does hyperphagia play a role in the development of childhood obesity? 2008-2009

This study is comparing the level of hyperphagia (overeating) between three important groups of obese children – those with simple lifestyle-related obesity, those with obesity associated with intellectual disability, and those with Prader-Willi Syndrome (a genetic disorder that causes over eating and other health problems).

Further understanding of the biological mechanisms behind the development of obesity in children would have enormous potential to inform clinical practice for individuals with lifestyle-related obesity.

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