Australian Paediatric Pharmacology Research Unit

The Australian Paediatric Research Unit (APPRU) conducts clinical trials in children to investigate the safety and efficacy of prescription drugs and medications typically developed for adults to assess and improve the safety and efficacy of such therapies for children.
We perform high quality, timely, clinical diagnosis diagnoses in children that comply with local and international best practice clinical guidelines. Our primary focus is always on the quality use of medicines in children.

We continue to provide clinical trials services and personnel who are highly experienced in Phase I to phase IV trials and issues relating to good clinical practice, Case Report Form (CRF) management and subject recruitment.

We also provided clinical pharmacology, research and development, clinical trial design and protocol development, good clinical practice compliance, pharmacokinetic and pharmacodynamic modelling and regulatory affairs strategies.

To find out more about APPRU, please visit our webpage

Our Services

Research Help

• Protocol Development
• Case Report Forms
• Recruitment
• Study conduct
• Study Evaluation

Specific areas of Expertise

• Pharmacokinetics
• Pharmacogenomics
• Complementary and Alternative Medicines
• Off-Label Prescribing
• Pharmacoeconomics
• Expertise in ethical issues surrounding paediatric trials
• Management of Good Clinical Practice (GCP)

We cover most areas of clinical research pharmacology, excluding oncology.

Contact Us

APPRU is located on the 5th floor of the new MCRI (AP) building across from the General Medicine department. The department can be accessed via either the blue or orange lifts and then through Speech Pathology towards the new MCRI (AP) building.

Associate Professor Noel Cranswick
Director of APPRU
Royal Children's Hospital
Flemington Road
Parkville Victoria 3052

T   +61 3 9345 6987
F   +61 3 9345 4825
E   noel.cranswick@rch.org.au

Shannon Kokoszka
Nurse Unit Manager
T   +61 3 9345 5570
F   +61 3 9345 4751