Dr David Burgner
Dr David Burgner
Group Leader/NHMRC Senior Research Fellow
NHFA Honorary Future Leader Fellow
Susceptibility to Paediatric Infection (SPIn)
Murdoch Childrens Research Institute
Royal Children's Hospital
Parkville Victoria 3052
T +61 3 9936 6730
David Burgner is a clinician and scientist in paediatric
infectious diseases. He trained in the UK and Australia and did his
PhD on host genetics and severe malaria at the University of Oxford
and in The Gambia, West Africa. His post-graduate training was at
Great Ormond Street Hospital and St Mary's Hospital, Imperial
College, London. From 2002-2010 he was the clinical lead for
paediatric infectious diseases and refugee child health, Child and
Adolescent Health Services, Western Australia and Associate
Professor of Paediatrics at the University of Western Australia. He
moved to Melbourne in 2010 and is currently based at MCRI and
Monash Children's, Southern Health.
Royal Australasian College of Physicians Excellence in
Mentorship: Academic and Research (2010)
NHMRC Clinical Career Development Fellowship (2010-13)
Australian Society for Infectious Diseases Frank Fenner Award for
Advanced Research in Infectious Diseases (2008)
Raine Medical Research Foundation Research Prize (commended)
Royal Australasian College of Physicians Servier Staff Fellowship
Member of the Editorial Boards: PLoS ONE, Genes, Pediatric
Infectious Diseases Journal, Infectious Diseases: Research and
Treatment and Journal of Pediatric Infectious Diseases
Board Member World Society for Paediatric Infectious Diseases
Committee Member, Australian and New Zealand Paediatric Infectious
Diseases Group (2010-)
United States Patent Application 61/051,721 filed 9 May 2008
'Kawasaki Disease'. Co-inventor
research focus & interest
David's overall research interests focus on understanding the
differential susceptibility and consequences to childhood infection
and inflammation, particularly in preterm infants and young
children. A particular interest is Kawasaki disease, a paediatric
vasculitis that damages the coronary arteries. He is co-lead of a
large international consortium investigating genetic factors in
Kawasaki disease and is also involved in epidemiological,
cardiovascular and immunological studies of Kawasaki disease in
Australia and overseas. He is currently developing projects that
investigate the broader role of childhood infection on chronic
vascular inflammation and atherosclerosis.
tier 1 and 2 publications
Khor CC, Davila S, Breunis WB, Lee Y-C, Shimizu C, Wright VJ,
Yeung RSM, Tan DEK, Kar KS, Wang JJ, Wong TY, Pang J, Paul Mitchell
P, Cimaz R, Dahdah N, Cheung YF, Huang GY, Yang W, Park I-S, Lee
J-K, Wu J-Y, Levin M‡, Burns JC‡, Burgner D‡, Kuijpers TW‡, Hibberd
ML‡ on behalf of the Hong Kong-Shanghai, Korean, Taiwan, U.S. and
International, Kawasaki Disease Genetics Consortiums. Genome-wide
association study identifies FCGR2A as a susceptibility factor for
Kawasaki disease. Nature Genetics ‡Joint senior and corresponding
Khor CC, Davila S, Shimizu, C, Sheng S, Matsubara T, Suzuki Y,
Newburger JW, Baker A, Burgner D, Breunis W, Kuijpers TW, Wright
VJ, Levin M, Hibberd ML, Burns JC, on behalf of US and
International Kawasaki Disease Genetics Consortia.. Genome wide
linkage and association mapping identify susceptibility alleles in
ABCC4 for Kawasaki disease. Journal of Medical Genetics.
Rye MS, Wiertsema SP, Scaman ES, Oommen J, Sun W, Francis RW, Ang
W, Pennell CE, Burgner D, Richmond P, Vijayasekaran S, Coates HL,
Brown SD, Blackwell JM, Jamieson SE. FBXO11, a regulator of the
TGFbeta pathway, is associated with severe otitis media in Western
Australian children. Genes Immun. 2011 Feb 3. [Epub ahead of
Currie AJ, Curtis S, Strunk T, Riley K, Liyanage K, Prescott S,
Doherty D, Simmer K, Richmond P, Burgner D. Preterm infants have
deficient monocyte and lymphocyte cytokine responses to group B
streptococcus. Infect Immun. 2011;79(4):1588-96.
Yim D, Ramsay J, Kothari D, Burgner D. Coronary artery dilatation
in toxic shock-like syndrome: the Kawasaki disease shock syndrome.
Pediatr Cardiol. 2010;31:1232-1235.
Woodland L, Burgner D, Paxton G, Zwi K. Health service delivery
for newly arrived refugee children: a framework for good practice.
J Paediatr Child Health. 2010;46:560-567.
Rye MS, Bhutta MF, Cheeseman MT, Burgner D, Blackwell JM, Brown
SD, Jamieson SE. Unraveling the genetics of otitis media: from
mouse to human and back again. Mamm Genome. 2010;22:66-82.5
Murray RJ, Davis JS, Burgner DP, Hansen-Knarhoi M, Krause V, Biggs
BA, Lemoh C, Benson J, Cherian S, Buttery J, Paxton G. The
Australasian Society for Infectious Diseases guidelines for the
diagnosis, management and prevention of infections in recently
arrived refugees: an abridged outline. Med J Aust.
Harnden A, Takahashi M, Burgner D. Kawasaki disease. BMJ.
Harnden A, Mayon-White R, Perera R, Yeates D, Goldacre M, Burgner
D. Kawasaki disease in England: ethnicity, deprivation, and
respiratory pathogens. Pediatr Infect Dis J. 2009;28:21-24.
Blyth CC, Best EJ, Jones CA, Nourse C, Goldwater PN, Daley AJ,
Burgner D, Henry G, Palasanthiran P. Nontuberculous mycobacterial
infection in children: a prospective national study. Pediatr Infect
Dis J. 2009;28:801-805.
Wright H, Waddington C, Geddes J, Newburger JW, Burgner D. Facial
nerve palsy complicating Kawasaki disease. Pediatrics.
Cherian S, Forbes D, Sanfilippo F, Cook A, Burgner D. The
epidemiology of Helicobacter pylori infection in African refugee
children resettled in Australia. Med J Aust.
Cherian S, Burgner D, Carson CF, Sanfilippo FM, Cook AG, Forbes
DA. Diagnosis of Helicobacter pylori infection in a high-prevalence
pediatric population: a comparison of 2 fecal antigen testing
methods and serology. J Pediatr Gastroenterol Nutr.
Zwi K, Raman S, Burgner D, Faniran S, Voss L, Blick B, Osborn M,
Borg C, Smith M. Towards better health for refugee children and
young people in Australia and New Zealand: The Royal Australasian
College of Physicians perspective. J Paediatr Child Health.
Moore H, Burgner D, Carville K, Jacoby P, Richmond P, Lehmann D.
Diverging trends for lower respiratory infections in non-Aboriginal
and Aboriginal children. J Paediatr Child Health.
Carville KS, Lehmann D, Hall G, Moore H, Richmond P, de Klerk N,
Burgner D. Infection is the major component of the disease burden
in aboriginal and non-aboriginal Australian children: a
population-based study. Pediatr Infect Dis J.
Peadon E, Burgner D, Nissen M, Buttery J, Zurynski Y, Elliott E,
Gold M, Marshall H, Booy R. Case for varicella surveillance in
Australia. J Paediatr Child Health. 2006;42:663-664.
Munns C, Zacharin MR, Rodda CP, Batch JA, Morley R, Cranswick NE,
Craig ME, Cutfield WS, Hofman PL, Taylor BJ, Grover SR, Pasco JA,
Burgner D, Cowell CT. Prevention and treatment of infant and
childhood vitamin D deficiency in Australia and New Zealand: a
consensus statement. Med J Aust. 2006;185:268-272.
Lee KY, Lee HS, Hong JH, Lee MH, Lee JS, Burgner D, Lee BC. Role
of prednisolone treatment in severe Mycoplasma pneumoniae pneumonia
in children. Pediatr Pulmonol. 2006;41:263-268.
Lee KY, Hong JH, Han JW, Lee JS, Lee BC, Burgner D. Features of
Kawasaki disease at the extremes of age. J Paediatr Child Health.
Burgner D, Jamieson SE, Blackwell JM. Genetic susceptibility to
infectious diseases: big is beautiful, but will bigger be even
better? Lancet Infect Dis. 2006;6:653-663.