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Health and fertility of young Men conceived using ICSI (HIM Study)

Research project

This project aims to learn more about the health, development, wellbeing and fertility of young men conceived using ICSI whose fathers either had a problem with sperm production or a blockage preventing the passage of sperm. A number of studies have assessed the health and development of ICSI-conceived children, but only one study so far worldwide has evaluated ICSI-conceived young adults aged more than 18 years.

We think it is extremely important to evaluate the health and fertility of young men conceived using ICSI because it is being used more and more frequently. More knowledge in this area will help us better inform couples who are struggling with infertility and assist fertility specialists worldwide.

We conducted a similar study in 2013 in Victoria that looked at the health and development of young adults conceived with standard IVF (without ICSI) compared to young adults conceived spontaneously. The study was well received by families, who were interested to know about the health and development of this group of young people. They felt it was acceptable to approach them many years after treatment had been completed, and 92% of young adults contacted participated in the study.

This project is being funded by a Partnership Grant through the National Health and Medical Research Council and the Hudson Institute of Medical Research, in conjunction with Victorian Assisted Reproductive Treatment Authority (VARTA), Monash IVF Group, Melbourne IVF, Fertility Society of Australia (FSA) and ACCESS. It has also previously been supported by the Monash IVF Research and Education Fund.

The ethical aspects of this research project have been approved by the Human Research and Ethics Committee of Monash Health (HREC #16316) and Melbourne IVF (HREC #56/17-MIVF). This project will be carried out according to the National Statement on Ethical Conduct in Human Research (2007) produced by the National Health and Medical Research Council of Australia.