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Victorian children will be amongst the first in Australia to have access to clinical genomic testing after the Victorian Clinical Genetics Services (VCGS) received accreditation from the National Association of Testing Authorities (NATA) for its whole-exome sequencing service. VCGS’s new accreditation means young children with serious genetic disorders will be able to access this revolutionary testing as part of their clinical care. Previously, whole-exome sequencing through Victorian testing laboratories was only available to patients involved in research studies. VCGS is based at the Murdoch Childrens Research Institute (MCRI) and joins only a handful of medical testing laboratories in Australia to hold this accreditation, and is the only site in Victoria to offer a fully accredited clinical genomics service. Exome sequencing uses a technology called Next Generation Sequencing which is different to traditional gene testing because it enables all 20,000 genes to be tested at the same time. The strength of...
Experts have identified a new treatment option that can be used to support adolescents with anorexia nervosa (AN). Researchers from the Murdoch Childrens Research Institute (MCRI), The Royal Children’s Hospital and the University of Melbourne compared the effectiveness of Parent-Focused Treatment (PFT) and Family-Based Treatment (FBT), the current standard of care for adolescents with AN. They found that there was a threefold increase in the odds of remission at the end of treatment in those who received PFT compared to FBT. The randomised control trial is the largest single site trial of family therapy for adolescents with AN. It reported on 107 patients, randomised to receive either PFT or FBT, between July 2010 and December 2015. The average age of participants was 15 years and 88 per cent were female. The average length of their illness was 10.5 months and more than one third were so unwell with AN that...
A resounding agreement was reached on three updates to Australian infant feeding advice by all participants, including key industry bodies at a recent Summit. The Centre for Food & Allergy Research (CFAR) Australian Infant Feeding Guidelines Summit was hosted by Murdoch Childrens Research Institute (MCRI) on Friday 13th May 2016. The Australasian Society for Clinical Immunology and Allergy (ASCIA) Guidelines provide advice and recommendations relevant to allergy prevention, on breastfeeding, the introduction of solids and supporting mothers and parents. The Centre for Food & Allergy Research (CFAR) is a national alliance of paediatric food allergy researchers and clinicians from 20 partner institutions across Australia. The Centre is coordinated from MCRI. Their collective research provides evidence to optimise food allergy management and find novel treatments. The 2016 CFAR Infant Feeding Summit is the second meeting on infant feeding. The initial roundtable was in August 2015 which summarised the research evidence on...
Heart muscle diseases are a leading cause of disability and death in children and adults but the causes remain poorly understood. The genetic changes that cause heart muscle disease are in the early stages of discovery. Identifying the genetic cause of heart disease is crucial in improving understanding of these conditions and for developing new drugs and therapies.
The Murdoch Childrens Research Institute (MCRI), in collaboration with innovation company Curve Tomorrow, is launching Bytes4Health. The program will offer digital health and medtech startups that are developing a product or interested in extending their technology into healthcare, a unique opportunity to access cutting edge medical research, clinical expertise and digital health product development experience. The Bytes4Health program will offer two companies the chance to be embedded within MCRI for four months. Companies will also receive $25,000 to go towards the development of their technology. They will work closely with research and clinical teams, including the Melbourne Childrens Trials Centre, a centre specialised in the evaluation and development of new healthcare products. They will also learn from the Curve Tomorrow team’s vast experience in developing products for healthcare professionals and patient communities. Dr James Dromey General Manager Business Development and Strategy at Murdoch Childrens Research Institute said, “Despite the growing...