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Muscle weakness in TPM3-myopathy is due to reduced Ca2+-sensitivity and impaired acto-myosin cross-bridge cycling in slow fibres.

Pubmed ID: 
26307083
Year: 
2015
Month: 
NOV
Volume: 
24
Issue: 
22
Citation: 
Yuen M, Cooper ST, Marston SB, Nowak KJ, McNamara E, Mokbel N, Ilkovski B, Ravenscroft G, Rendu J, de Winter JM, Klinge L, Beggs AH, North KN, Ottenheijm CA, Clarke NF. Muscle weakness in TPM3-myopathy is due to reduced Ca2+-sensitivity and impaired acto-myosin cross-bridge cycling in slow fibres. HUMAN MOLECULAR GENETICS 24 (22) : 6278 - 92(2015) PubMed (Grant IDs: APP571287, APP1022707, APP1048816, APP1035955)