Age, sex, and shared family factors, including diet, contribute to variation in plasma concentrations of TMAO and its precursors in the Growing Up in Australia’s Child Health Checkpoint.
- Andraos S, Lange K, Clifford SA, Jones B, Thorstensen EB, Kerr JA, et al. Plasma Trimethylamine N-Oxide and Its Precursors: Population Epidemiology, Parent–Child Concordance, and Associations with Reported Dietary Intake in 11- to 12-Year-Old Children and Their Parents, Current Developments in Nutrition, Volume 4, Issue 7, July 2020, nzaa103, https://doi.org/10.1093/cdn/nzaa103
Frequent takeaway food, and to a lesser degree sugar-sweetened beverage consumption, is associated with adverse preclinical cardiovascular phenotypes in adults. Lack of such associations in children highlights opportunities for prevention of disease.
- Saraf S, Grobler A, Liu RS, Liu M, Wake M, Olds T, et al. Takeaway food, sugar-sweetened beverages and preclinical cardiometabolic phenotypes in children and adults. European Journal of Preventive Cardiology, 2020. zwaa070, https://doi.org/10.1093/eurjpc/zwaa070
This study describes the Goldilocks “just right” daily durations of physical activity (moderate-to-vigorous and light intensities), sedentary time and sleep that are associated with the best skeletal health in children.
- Dumuid D, Simm P, Wake M, Burgner D, Juonala M, Wu F, et al. The "Goldilocks Day" for Children's Skeletal Health: Compositional Data Analysis of 24-Hour Activity Behaviors. J Bone Miner Res. 2020 Jul 30. doi: 10.1002/jbmr.4143. Epub ahead of print. PMID: 32730680.
MVPA is 2 to 6 times as potent as sleep or sedentary time for children’s health: a 0.1SD decrease in adiposity is associated with 52 minutes more sleep or 56 minutes less sitting, which is equivalent to just 17 minutes more MVPA.
- Ng E, Wake M, Olds T, Lycett K, Edwards B, Le H, Dumuid D. Equivalence Curves for Healthy Lifestyle Choices. Pediatrics. 2021 Mar 26:e2020025395. doi: 10.1542/peds.2020-025395. Epub ahead of print. PMID: 33771915.