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The PEAT Trial

What is PEAT?

We are studying egg oral immunotherapy in combination with probiotics to see if it is effective in treating children with egg allergy. 
 
 

Egg allergy is one of the most common food allergies in childhood affecting almost 9 per cent of babies in Australia and up to 2.5 per cent of children worldwide. Because eggs are a common cooking ingredient, accidental ingestion is common, causing frequent and sometimes life-threatening reactions.

Currently the standard of care for treatment of egg allergy is the total avoidance of egg. We want to see if probiotic food immunotherapy is effective in treating egg allergies.

Who can take part?

Children:
  • Aged 5-17 years
  • Allergic to hen’s egg


What will I be asked to do?

  • For this study, the children will be randomly allocated into one of two groups. Half the children will go into an active group (probiotic and egg oral immunotherapy) and half will go into a placebo group. The placebo group will not receive active ingredients. Neither families nor the MCRI researchers will know who is in the active group and who is in the placebo group. 
  • Multiple visits to MCRI will be required. At home the child will take a dose of probiotic (or placebo) and a dose of egg powder (or placebo) once a day for a total of 18 months.

How can I find out more?

 

If you have any questions about the study please contact egg.study@mcri.edu.au