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Projects

Research project
Project overview More than two per cent of Victorian children up to the age of 11 are diagnosed with autism, with 30 per cent of those said to have lost language and social skills over time. Of those who lose skills, a smaller proportion will experience substantial regression over a period of just weeks or months. Little is known about the causes of this severe and rapid loss of skills. The MCRI’s Loss of Skills study will collect high quality information about children with autism or social and communication impairments consistent with autism who have substantial loss of skills. By focusing on children up to age seven, researchers hope to discover possible causes as well as describe clinical subtypes of loss of skills, and to be able to link the two. Who can participate? Children who live in Victoria diagnosed with autism or who have social communication impairments consistent with ...
Research project
Mild Matters is a research project which aims to find out if hearing aids can help babies and young children with bilateral mild hearing loss. Babies can be born with different degrees of hearing loss. Hearing aids can help babies with moderate or greater degrees of hearing loss, but we do not know whether they help babies with mild hearing loss. This study helps us answer this important question. Throughout 2018 and 2019, we are inviting babies and children to take part in this project who: have mild permanent hearing loss in both ears are less than 2 years old are from NSW, QLD or VIC have been diagnosed within the last three months If you are interested in taking part in this study or have any questions about the research, please contact the Mild Matters research team on 03 9345-6180 or mild.matters@mcri.edu.au .
Research project
The HearS-cCMV project team is working with the Victorian Infant Hearing Screening Program (VIHSP) to provide additional services to Victorian families. This project involves an extra test for babies who do not pass their second hearing screen who are born at selected Victorian hospitals: The Royal Women’s Hospital, Parkville The Mercy Hospital for Women, Heidelberg The Monash Medical Centre, Clayton Sunshine Hospital, Western Health, Sunshine Video instructions for taking a saliva swab This extra test uses a sample of the baby’s mouth saliva (spit) to see if there was a virus (germ) called cytomegalovirus (CMV) present at the time of their birth. If the virus is present from birth it is called congenital CMV. For a very small number of babies, congenital CMV can be the cause of life-long hearing loss. For some of these babies, there may be a treatment available if the doctors know this virus is present ...
Research project
This project aims to learn more about the health, development, wellbeing and fertility of young men conceived using ICSI whose fathers either had a problem with sperm production or a blockage preventing the passage of sperm. A number of studies have assessed the health and development of ICSI-conceived children, but only one study so far worldwide has evaluated ICSI-conceived young adults aged more than 18 years. We think it is extremely important to evaluate the health and fertility of young men conceived using ICSI because it is being used more and more frequently. More knowledge in this area will help us better inform couples who are struggling with infertility and assist fertility specialists worldwide. We conducted a similar study in 2013 in Victoria that looked at the health and development of young adults conceived with standard IVF (without ICSI) compared to young adults conceived spontaneously. The study was well received ...
Research project
What is Vitality? There has been an increase in food allergy in recent years. The cause of this is unknown; however, the number of people experiencing allergic reactions has significantly increased. The aims of this study are to see the relationship between food allergy, vitamin D and immune function in infants. Who can take part? Mothers with infants: Age 6-12 weeks Planning to be primarily breastfed until 6 months of age (not exclusively bottle-fed) Living in Greater Melbourne, Victoria Who cannot take part? Infants already receiving vitamin D supplementation Infants born under 37 weeks gestation, under 2.5kg or with a significant medical problem What will I be asked to do? Participate in one initial home visit where we will collect samples. Complete 4 online surveys in your child’s first year of life. Attend a free allergy test appointment when your child turns one year old at the Royal Children’s Hospital. ...
Research project
CardioRegen The Melbourne Children’s Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen) is an integrated clinical and research program across the Melbourne Children’s Campus and Parkville Precinct. Our vision is to transform the clinical care of patients with childhood heart disease by bringing together researchers across the translational continuum from discovery science to the clinic. CardioRegen encompasses three major research programs in Diagnostics, Discovery and Translation, which are broadly focused on understanding the genetic causes of childhood heart disease and developing novel regenerative therapies for children with heart failure. Childhood Heart Disease and Heart Failure Heart disease is the leading cause of death and disability in children, affecting up to 1 in 100 live births. Complex forms of childhood heart disease (CHD) often require multiple surgical interventions during early childhood and adolescence. Surgical advances over the past 20 years have dramatically increased survival rates, with more than 85% of children ...
Research project
About the Australian and New Zealand Childhood Arthritis Risk factor Identification STudY (ANZ-CLARITY) In this research project, we are establishing a national juvenile idiopathic arthritis (JIA) biobank, called ANZ-CLARITY (Australian and New Zealand ChiLdhood Arthritis Risk factor Identification sTudY). The ANZCLARITY study working to better understand the form of childhood arthritis called JIA in hopes of improving care, identifying cause, and eventually, finding a cure. JIA belongs to a group of illnesses called autoimmune diseases. Your body has an immune system, which fights germs and keeps you healthy. In autoimmune diseases the body’s immune system mistakes a normal part of the body for something foreign (like a germ), and starts attacking the body itself. In JIA the immune system attacks the joints and sometimes other body tissues. This is called an autoimmune process and we do not understand exactly how and why this happens. The symptoms of JIA are joint ...
Research project
Unlocking the secrets of hearing loss VicCHILD is the Victorian Childhood Hearing Impairment Longitudinal Databank. It's a Victorian register and research databank of children born with a permanent hearing loss. VicCHILD ultimately aims to help children with permanent hearing loss reach their full potentials. VicCHILD is based at the Royal Children's Hospital in Melbourne. Update your contact details Register your interest in VicChild As of March 2020, over 950 Victorian families have already contributed data to VicCHILD. The databank holds a range of information about all Victorian children born with a permanent hearing loss. The information collected and stored by VicCHILD will: help researchers and health professionals gain a better understanding of the causes and outcomes of childhood hearing loss help researchers understand why some children with a hearing loss do well, while others face greater difficulties improve intervention and treatment and ultimately the lives of children with permanent hearing ...
Research project
Traumatic Brain Injury (TBI) is one of the leading causes of death and disability in children and adolescents worldwide. TBI refers to any damage to the brain acquired as a result of a trauma, i.e., injuries caused by external forces such as falls, contact sports, and accidents. TBI can cause an interruption to a child’s development. It can result in significant impairments such as memory holding information in the mind, and making decisions. Problems in these areas may affect academic skills, setting goals, and completing everyday tasks. Researchers at the Murdoch Children’s Research Institute, Royal Children’s Hospital, and University of Melbourne are conducting a trial to investigate the impact of computer activities and their effectiveness in improving memory and making decisions in children post TBI. We are looking for children and adolescents aged 7- 15 years old, who have experienced a TBI. Participation in this research will involve completing questionnaires ...
Research project
***The GPC STUDY is looking for students, click here for more information and to apply*** About the Study The Group Pregnancy Care study is implementing and evaluating a new approach to antenatal and postnatal care that involves inter-agency collaboration between public maternity hospitals, refugee settlement agencies, and maternal and child health (MCH) services. The aim of the program is to provide multifaceted, culturally appropriate preventive health care, information and support to refugee women during and after pregnancy in a group setting. The program is cost-free; provides care and information that is woman-directed, culturally appropriate and in women’s language; and facilitates links and referrals to services as necessary. For information about the different Group Pregnancy Care sites click on the link: Healthy Happy Beginnings, Karen families in Werribee Happy Mothers, Assyrian Chaldean Families in Craigieburn Program Principles The organisations and staff involved have agreed to apply these principles: Community consultation and ...