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Projects

Research project
PETS is a research project being conducted by the Murdoch Children's Research Institute at The Royal Children's Hospital, Melbourne. PETS is a study of twins, from when they were in the womb through to childhood and beyond. We aim to work out what makes us all who we are; our health, development and wellbeing. We have chosen to start our research with twins, who share the same mother, but are usually in their own 'sac' during pregnancy, then share the same home environment as children. Despite this, even 'identical' twins can have different personalities, physical characteristics and illnesses. We want to know why these differences exist and what they can tell us about the first years of life. It would be of great value to us if you have any suggestions or comments you would like to make about our research and what research questions interests you. Your comments could ...
Research project
About the Australian and New Zealand Childhood Arthritis Risk factor Identification STudY (ANZ-CLARITY) In this research project, we are establishing a national juvenile idiopathic arthritis (JIA) biobank, called ANZ-CLARITY (Australian and New Zealand ChiLdhood Arthritis Risk factor Identification sTudY). The ANZCLARITY study working to better understand the form of childhood arthritis called JIA in hopes of improving care, identifying cause, and eventually, finding a cure. JIA belongs to a group of illnesses called autoimmune diseases. Your body has an immune system, which fights germs and keeps you healthy. In autoimmune diseases the body’s immune system mistakes a normal part of the body for something foreign (like a germ), and starts attacking the body itself. In JIA the immune system attacks the joints and sometimes other body tissues. This is called an autoimmune process and we do not understand exactly how and why this happens. The symptoms of JIA are joint ...
Research project
The newly established Australian Hand Difference Register (AHDR) is a database of children born with a hand difference and/or arm difference. The AHDR is managed by researchers at the Murdoch Children’s Research Institute, which is located at The Royal Children’s Hospital in Melbourne. To begin with, the AHDR will focus on children attending The Royal Children’s Hospital, before being extended within Victoria, and then Australia-wide. The AHDR aims to: find out how many children are born with a hand/arm difference in Australia learn more about possible causes and risk factors gain information to help plan services identify possible participants for future research The AHDR is currently funded by Aussie Hands ( The Aussie Hands Foundation Inc. ), a support group for people who have a hand difference and their families, and additional funding has been obtained from the Australasian Foundation for Plastic Surgery . Funding organisations do not have access ...
Research project
CardioRegen Improving the lives of kids with heart disease The Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen) is a research centre focused on improving the lives of patients with childhood heart disease (CHD). Our team of researchers and clinicians use genomics and stem cell medicine to understand the causes of CHD and for the discovery of new treatments. For more information head to our CardioRegen project website !
Research project
Why are survivors of childhood cancer 15 times more likely to have heart failure? How can the incidence of cardiovascular disease, which is 8 times higher in childhood cancer survivors than the general population be reduced? How do we identify at risk patients earlier and provide the best management regimen to improve the long-term cardiovascular health of these children and AYA? ACOR is a world first paediatric and young adult prospective cardio-oncology registry designed to capture the clinical, epidemiological and pharmaceutical data from every Australian child and young adult that receives cardiac toxic therapies (chemotherapy, radiotherapy, molecular and immunotherapy). This strategically places ACOR in a position to provide data to underpin research and generate hypotheses that will address some of the above questions. About ACOR aims to provide a research platform from which longitudinal data can be attained and through which further research can be developed to better provide outcomes ...
Research project
Brain, cognition, mental health and functional outcomes in Type 1 diabetes – ~thirty year follow-up of the Royal Children’s Hospital Cohort What is the project about? We are conducting research examining the impact of Type 1 Diabetes on long-term brain, cognitive, mental health and functional outcomes. In order to interpret our results, we need to compare the outcomes of our Type 1 Diabetes participants with a group of healthy individuals of similar age. We are looking for adults who are happy to be part of this healthy control group! Who can take part? Individuals who are: aged between 28 – 44 years willing to attend a one off assessment appointment at MCRI (approximately 3.5 hours) Who cannot take part? Individuals with: a history of neurological illness history of brain injury current chronic illness What will I be asked to do? Complete a short questionnaire asking questions about your education, employment ...
Research project
The Children’s Cancer Centre Tissue Bank is a world-class resource for researchers studying childhood and adolescent/young adult (AYA) cancer. The Tissue Bank is based at the Murdoch Children's Research Institute and The Royal Children’s Hospital (RCH). Our Tissue Bank also includes patients with bone marrow disorders, primary immunodeficiency disease and Neurofibromatosis.