Associate Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation for Stem Cell Medicine (reNEW). David co-directs, with Associate Professor Rachel Conyers, the Australian Cardio-Oncology Registry (ACOR), a national program targeted at improving long-term cardiac health outcomes for childhood cancer survivors. The focus of Associate Professor Elliott’s laboratory is to develop pluripotent stem cell-based models of heart disease and use these models to find new therapies for heart disease. Throughout his career Assoc. Prof. Elliott has made important contributions to understanding the molecular control of heart muscle development, function and disease.
Associate Professor David Elliott completed his PhD on the genetics of heart development at The Victor Chang Cardiac Research Institute and The Walter and Eliza Hall Institute. He continued to post-doctoral studies at the University of Cambridge studying the nervous system in the fruit fly at the Wellcome Trust/Cancer Research UK Gurdon Institute. Associate Professor Elliott began using human pluripotent stem cells in a second post-doc with Professors Andrew Elefanty and Ed Stanley at Monash University where he generated key stem cell lines and identified the first cardiac lineage cell surface markers.
Associate Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation for Stem Cell Medicine (reNEW). David co-directs, with Associate...
Associate Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation for Stem Cell Medicine (reNEW). David co-directs, with Associate Professor Rachel Conyers, the Australian Cardio-Oncology Registry (ACOR), a national program targeted at improving long-term cardiac health outcomes for childhood cancer survivors. The focus of Associate Professor Elliott’s laboratory is to develop pluripotent stem cell-based models of heart disease and use these models to find new therapies for heart disease. Throughout his career Assoc. Prof. Elliott has made important contributions to understanding the molecular control of heart muscle development, function and disease.
Associate Professor David Elliott completed his PhD on the genetics of heart development at The Victor Chang Cardiac Research Institute and The Walter and Eliza Hall Institute. He continued to post-doctoral studies at the University of Cambridge studying the nervous system in the fruit fly at the Wellcome Trust/Cancer Research UK Gurdon Institute. Associate Professor Elliott began using human pluripotent stem cells in a second post-doc with Professors Andrew Elefanty and Ed Stanley at Monash University where he generated key stem cell lines and identified the first cardiac lineage cell surface markers.
Top Publications
Conyers, R, Devaraja, S, Elliott, D.
Systematic review of pharmacogenomics and adverse drug reactions in paediatric oncology patients.
Pediatric Blood & Cancer
65(4)
:
2018
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Correia, C, Koshkin, A, Duarte, P, Hu, D, Carido, M, Sebastião, MJ, Gomes‐Alves, P, Elliott, DA, Domian, IJ, Teixeira, AP, et al.
3D aggregate culture improves metabolic maturation of human pluripotent stem cell derived cardiomyocytes.
Biotechnology and Bioengineering
115(3)
:
630 -644
2018
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Yamauchi, K, Li, J, Morikawa, K, Liu, L, Shirayoshi, Y, Nakatsuji, N, Elliott, DA, Hisatome, I, Suemori, H.
Isolation and characterization of ventricular-like cells derived from NKX2-5 eGFP/w and MLC2v mCherry/w double knock-in human pluripotent stem cells.
Biochemical and Biophysical Research Communications
495(1)
:
1278 -1284
2018
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Mills, RJ, Titmarsh, DM, Koenig, X, Parker, BL, Ryall, JG, Quaife-Ryan, GA, Voges, HK, Hodson, MP, Ferguson, C, Drowley, L, et al.
Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest.
Proceedings of the National Academy of Sciences of the United States of America
114(40)
:
e8372 -e8381
2017
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Conyers, R, Costello, B, La Gerche, A, Tripaydonis, A, Burns, C, Ludlow, L, Lange, P, Ekert, P, Mechinaud, F, Cheung, M, et al.
Chemotherapy‐related cardiotoxicity: are Australian practitioners missing the point?.
Internal Medicine Journal
47(10)
:
1166 -1172
2017
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