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Details

Role Theme Director - Stem Cell Biology
Research area Stem Cell Medicine

Contact

Available for student supervision
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.

Top Publications

  • Porrello, ER, Johnson, BA, Aurora, AB, Simpson, E, Nam, Y-J, Matkovich, SJ, Dorn, GW, van Rooij, E, Olson, EN. miR-15 Family Regulates Postnatal Mitotic Arrest of Cardiomyocytes. Circulation Research 109(6) : 670 -679 2011
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  • Charchar, FJ, Porrello, E, Delbridge, LM, Harrap, SB. THE ROLE OF MICRORNA IN CARDIAC HYPERTROPHY INDEPENDENT OF BLOOD PRESSURE. Journal of Hypertension 29: e42 2011
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  • Porrello, ER, Olson, EN. Building a New Heart From Old Parts. Circulation Research 107(11) : 1292 -1294 2010
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  • Gezmish, O, Tare, M, Parkington, HC, Morley, R, Porrello, ER, Bubb, KJ, Black, MJ. Maternal Vitamin D Deficiency Leads to Cardiac Hypertrophy in Rat Offspring. Reproductive Sciences 17(2) : 168 -176 2010
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  • Porrello, ER, Meeker, WF, Thomas, WG, Widdop, RE, Delbridge, LMD. Glucocorticoids Suppress Growth in Neonatal Cardiomyocytes Co-Expressing AT2 and AT1 Angiotensin Receptors. Neonatology 97(3) : 257 -265 2010
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