Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Top Publications
Porrello, ER, Johnson, BA, Aurora, AB, Simpson, E, Nam, Y-J, Matkovich, SJ, Dorn, GW, van Rooij, E, Olson, EN.
miR-15 Family Regulates Postnatal Mitotic Arrest of Cardiomyocytes.
Circulation Research
109(6)
:
670 -679
2011
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Charchar, FJ, Porrello, E, Delbridge, LM, Harrap, SB.
THE ROLE OF MICRORNA IN CARDIAC HYPERTROPHY INDEPENDENT OF BLOOD PRESSURE.
Journal of Hypertension
29:
e42
2011
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Porrello, ER, Olson, EN.
Building a New Heart From Old Parts.
Circulation Research
107(11)
:
1292 -1294
2010
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Gezmish, O, Tare, M, Parkington, HC, Morley, R, Porrello, ER, Bubb, KJ, Black, MJ.
Maternal Vitamin D Deficiency Leads to Cardiac Hypertrophy in Rat Offspring.
Reproductive Sciences
17(2)
:
168 -176
2010
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Porrello, ER, Meeker, WF, Thomas, WG, Widdop, RE, Delbridge, LMD.
Glucocorticoids Suppress Growth in Neonatal Cardiomyocytes Co-Expressing AT2 and AT1 Angiotensin Receptors.
Neonatology
97(3)
:
257 -265
2010
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