Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Top Publications
Harrap, S, Charchar, F, Porrello, E, Delbridge, L.
Cardiac MicroRNAs and the Predisposition to Polygenic Cardiac Hypertrophy.
Heart Lung and Circulation
19:
s48
2010
view publication
Porrello, ER, Delbridge, LMD.
Cardiomyocyte autophagy is regulated by angiotensin II type 1 and type 2 receptors.
Autophagy
5(8)
:
1215 -1216
2009
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Porrello, ER, D'Amore, A, Curl, CL, Allen, AM, Harrap, SB, Thomas, WG, Delbridge, LMD.
Angiotensin II Type 2 Receptor Antagonizes Angiotensin II Type 1 Receptor–Mediated Cardiomyocyte Autophagy.
Hypertension
53(6)
:
1032 -1040
2009
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Porrello, ER, Bell, JR, Schertzer, JD, Curl, CL, McMullen, JR, Mellor, KM, Ritchie, RH, Lynch, GS, Harrap, SB, Thomas, WG, et al.
Heritable pathologic cardiac hypertrophy in adulthood is preceded by neonatal cardiac growth restriction.
AJP Regulatory Integrative and Comparative Physiology
296(3)
:
r672 -r680
2009
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Porrello, ER, Delbridge, LMD, Thomas, WG.
The angiotensin II type 2 (AT2) receptor: an enigmatic seven transmembrane receptor..
Frontiers in Bioscience-Landmark
14(3)
:
958 -972
2009
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