Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Top Publications
Porrello, ER, Delbridge, LMD.
HFpEF—Time to Explore the Role of Genetic Heterogeneity in Phenotypic Variability.
Circulation
140(20)
:
1607 -1609
2019
view publication
Konstantinov, IE, Fricke, TA, Ivanov, Y, Porrello, E.
Commentary: From bioprosthetic tissue degeneration to regeneration: A new surgical horizon in the era of regenerative medicine.
Journal of Thoracic and Cardiovascular Surgery
158(3)
:
742 -743
2019
view publication
Wilson, CH, Bywater, MJ, Burkhart, DL, Sabò, A, Straube, J, Pendino, V, Hudson, JE, Quaife-Ryan, GA, Porrello, ER, Kress, TR, et al.
Abstract 108: Reactivation of Myc Transcription in the Heart Unlocks its Proliferative Capacity.
Circulation Research
125(Suppl_1)
:
2019
view publication
Nagareddy, P, Sreejit, G, Abdel-Latif, A, Athmanathan, B, Annabathula, R, Dhyani, A, Noothi, S, Quaife-Ryan, G, Hudson, J, Smyth, S, et al.
Nlrp3 Inflammasome-Primed Neutrophils Return To The Bone Marrow To Propagate Granulopoiesis Following Myocardial Injury.
Atherosclerosis
287:
e22
2019
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Mills, RJ, Parker, BL, Monnot, P, Needham, EJ, Vivien, CJ, Ferguson, C, Parton, RG, James, DE, Porrello, ER, Hudson, JE.
Development of a human skeletal micro muscle platform with pacing capabilities.
Biomaterials
198:
217 -227
2019
view publication