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Details

Role Esteemed Honorary Fellow
Research area Stem Cell Medicine
Group Blood Development

Contact

Available for student supervision
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research is aimed at understanding the molecular basis of these disorders to improve diagnosis and counselling, identify new therapeutic targets and test the effectiveness of new treatments to ultimately improve the quality of life for children with these debilitating conditions
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s...
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research is aimed at understanding the molecular basis of these disorders to improve diagnosis and counselling, identify new therapeutic targets and test the effectiveness of new treatments to ultimately improve the quality of life for children with these debilitating conditions

Top Publications

  • Belluoccio, D, Etich, J, Rosenbaum, S, Frie, C, Grskovic, I, Stermann, J, Ehlen, H, Vogel, S, Zaucke, F, von der Mark, K, et al. Sorting of growth plate chondrocytes allows the isolation and characterization of cells of a defined differentiation status.. J Bone Miner Res 25(6) : 1267 -1281 2010
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  • Kannu, P, Bateman, JF, Randle, S, Cowie, S, du Sart, D, McGrath, S, Edwards, M, Savarirayan, R. Premature arthritis is a distinct type II collagen phenotype.. Arthritis Rheum 62(5) : 1421 -1430 2010
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  • Belluoccio, D, Grskovic, I, Niehoff, A, Schlötzer-Schrehardt, U, Rosenbaum, S, Etich, J, Frie, C, Pausch, F, Moss, SE, Pöschl, E, et al. Deficiency of annexins A5 and A6 induces complex changes in the transcriptome of growth plate cartilage but does not inhibit the induction of mineralization.. J Bone Miner Res 25(1) : 141 -153 2010
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  • Zreiqat, H, Belluoccio, D, Smith, MM, Wilson, R, Rowley, LA, Jones, K, Ramaswamy, Y, Vogl, T, Roth, J, Bateman, JF, et al. S100A8 and S100A9 in experimental osteoarthritis.. Arthritis Res Ther 12(1) : R16 2010
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  • Rajpar, MH, McDermott, B, Kung, L, Eardley, R, Knowles, L, Heeran, M, Thornton, DJ, Wilson, R, Bateman, JF, Poulsom, R, et al. Targeted induction of endoplasmic reticulum stress induces cartilage pathology.. PLoS Genet 5(10) : e1000691 2009
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