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Details

Role Esteemed Honorary Fellow
Research area Stem Cell Medicine
Group Blood Development

Contact

Available for student supervision
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research is aimed at understanding the molecular basis of these disorders to improve diagnosis and counselling, identify new therapeutic targets and test the effectiveness of new treatments to ultimately improve the quality of life for children with these debilitating conditions
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s...
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research is aimed at understanding the molecular basis of these disorders to improve diagnosis and counselling, identify new therapeutic targets and test the effectiveness of new treatments to ultimately improve the quality of life for children with these debilitating conditions

Top Publications

  • Campos-Xavier, AB, Martinet, D, Bateman, J, Belluoccio, D, Rowley, L, Tan, TY, Baxová, A, Gustavson, K-H, Borochowitz, ZU, Innes, AM, et al. Mutations in the heparan-sulfate proteoglycan glypican 6 (GPC6) impair endochondral ossification and cause recessive omodysplasia.. Am J Hum Genet 84(6) : 760 -770 2009
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  • Ishida, Y, Yamamoto, A, Kitamura, A, Lamandé, SR, Yoshimori, T, Bateman, JF, Kubota, H, Nagata, K. Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection.. Mol Biol Cell 20(11) : 2744 -2754 2009
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  • Allen, JM, Zamurs, L, Brachvogel, B, Schlötzer-Schrehardt, U, Hansen, U, Lamandé, SR, Rowley, L, Fitzgerald, J, Bateman, JF. Mice lacking the extracellular matrix protein WARP develop normally but have compromised peripheral nerve structure and function.. J Biol Chem 284(18) : 12020 -12030 2009
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  • Wilson, R, Whitelock, JM, Bateman, JF. Proteomics makes progress in cartilage and arthritis research.. Matrix Biol 28(3) : 121 -128 2009
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  • Cameron, TL, Belluoccio, D, Farlie, PG, Brachvogel, B, Bateman, JF. Global comparative transcriptome analysis of cartilage formation in vivo.. BMC Dev Biol 9: 20 2009
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