Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research is aimed at understanding the molecular basis of these disorders to improve diagnosis and counselling, identify new therapeutic targets and test the effectiveness of new treatments to ultimately improve the quality of life for children with these debilitating conditions
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s...
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research is aimed at understanding the molecular basis of these disorders to improve diagnosis and counselling, identify new therapeutic targets and test the effectiveness of new treatments to ultimately improve the quality of life for children with these debilitating conditions
Top Publications
Wilson, R, Bateman, JF.
A robust method for proteomic characterization of mouse cartilage using solubility-based sequential fractionation and two-dimensional gel electrophoresis..
Matrix Biol
27(8)
:
709 -712
2008
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Belluoccio, D, Rowley, L, Fosang, A, Little, C, Bateman, JF.
217 GLOBAL GENE EXPRESSION PROFILING OF EARLY OSTEOARTHRITIS IN WILD-TYPE MICE AND MICE LACKING ADAMTS-5 ACTIVITY.
Osteoarthritis and Cartilage
16:
s103
2008
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Zreiqat, H, Belluoccio, D, Smith, MM, Roth, J, Vogl, T, Bateman, JF, Little, CB.
144 S100A8/S100A9 PROTEINS PLAY A ROLE IN CARTILAGE DEGENERATION IN OSTEOARTHRITIS.
Osteoarthritis and Cartilage
16:
s75
2008
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Belluoccio, D, Wilson, R, Rowley, L, Bateman, J.
213 EXPRESSION PROFILING OF MOUSE FEMORAL HEAD EXPLANT CULTURES AFTER STIMULATION WITH INTERLEUKIN-1α OR RETINOIC ACID.
Osteoarthritis and Cartilage
16:
s101
2008
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Cameron, TL, Belluoccio, D, Brachvogel, B, Farlie, PG, Bateman, JF.
218 GENOME-WIDE COMPARATIVE TRANSCRIPTOME ANALYSIS OF CARTILAGE FORMATION IN VIVO.
Osteoarthritis and Cartilage
16:
s103
2008
view publication