John Carlin has an international reputation in biostatistics, the discipline underpinning the use of statistical methods for designing and analysing quantitative studies in health and medical research. He has been involved in a wide range of areas, especially relating to child and adolescent health research (including allergy and asthma, cystic fibrosis, cardiac disease, neonatology, rotavirus disease, vaccines, and adolescent mental health and behaviour) while his methodological research has focussed on methods for handling incompleteness in data and (more recently) causal inference. He has strong interests in the public and scientific usage and understanding of statistical methods and concepts (such as the widely misunderstood idea of "statistical significance") and also has long-standing interests in Bayesian statistical methods. Prof. Carlin has been based at the Melbourne Children's campus since 1991, and was head of the Clinical Epidemiology and Biostatistics Unit within the Murdoch Children's Research Institute (also supported by the University of Melbourne Department of Paediatrics) for 21 years until 2022. He also holds an honorary professorial appointment within the Department of Paediatrics, along with an appointment in the University of Melbourne's School of Population & Global Health since 2002. In the latter role he established the Master of Biostatistics program at the University of Melbourne, in conjunction with the Biostatistics Collaboration of Australia, which he co-­founded. Since 2012 he has led the Victorian Centre for Biostatistics (ViCBiostat), a collaboration between the MCRI, University of Melbourne and Monash University, which was established under a Centre of Research Excellence grant from the National Health & Medical Research Council to conduct research and provide advanced training in biostatistics. In 2018 he was elected Fellow of the Australian Academy of Health and Medical Sciences.