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Details

Role Group Leader / Snr Princ Research Fellow
Research area Clinical Sciences

Contact

Available for student supervision
Dr Seal trained as a clinical neuropsychologist and has over 15 years experience in coordinating neuroimaging investigations of brain development. After completing his PhD he was awarded a Wellcome Trust International Fellowship (2001-2002) to support a two-year postdoctoral position in the Section of Neuroimaging, Institute of Psychiatry(IOP), Kings College London. Subsequently, Dr Seal was able to obtain a NARSAD Young Investigator Award (2003-2005) to continue his postdoctoral training in neuroimaging. In 2005 Dr Seal returned to Australia as a member of the Senior Research Group at The Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne. In this position he coordinated several large investigations measuring changes in brain structure and function across the life-span. On the basis of this work he was awarded the Ronald Phillip Griffith Fellowship (2007-2009). From 2007-2010 he successfully coordinated onsite Australia’s largest study investigating the neurocognitive impact of heavy cannabis use on brain development (NHMRC Project 459111).

In 2010 he was was appointed Group Leader of the Developmental Imaging research group at the Murdoch Children's Research Institute. In this role he is responsible for coordinating and facilitating research utilising the Research MRI Scanner and supervises a multidisciplinary team of clinicians, MRI technologists and neuroscientists. He is currently involved in several ongoing studies of neurodevelopment including as Chief Investigator on NHMRC Project Grants and ARC Discovery Grants. He holds a joint appointment (0.5) as a Principal Research Fellow in the Department of Paediatrics, The University of Melbourne
Dr Seal trained as a clinical neuropsychologist and has over 15 years experience in coordinating neuroimaging investigations of brain development. After completing his PhD he was awarded a Wellcome Trust International Fellowship (2001-2002) to support...
Dr Seal trained as a clinical neuropsychologist and has over 15 years experience in coordinating neuroimaging investigations of brain development. After completing his PhD he was awarded a Wellcome Trust International Fellowship (2001-2002) to support a two-year postdoctoral position in the Section of Neuroimaging, Institute of Psychiatry(IOP), Kings College London. Subsequently, Dr Seal was able to obtain a NARSAD Young Investigator Award (2003-2005) to continue his postdoctoral training in neuroimaging. In 2005 Dr Seal returned to Australia as a member of the Senior Research Group at The Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne. In this position he coordinated several large investigations measuring changes in brain structure and function across the life-span. On the basis of this work he was awarded the Ronald Phillip Griffith Fellowship (2007-2009). From 2007-2010 he successfully coordinated onsite Australia’s largest study investigating the neurocognitive impact of heavy cannabis use on brain development (NHMRC Project 459111).

In 2010 he was was appointed Group Leader of the Developmental Imaging research group at the Murdoch Children's Research Institute. In this role he is responsible for coordinating and facilitating research utilising the Research MRI Scanner and supervises a multidisciplinary team of clinicians, MRI technologists and neuroscientists. He is currently involved in several ongoing studies of neurodevelopment including as Chief Investigator on NHMRC Project Grants and ARC Discovery Grants. He holds a joint appointment (0.5) as a Principal Research Fellow in the Department of Paediatrics, The University of Melbourne

Top Publications

  • Bhattacharyya, S, Crippa, JA, Allen, P, Martin-Santos, R, Borgwardt, S, Fusar-Poli, P, Rubia, K, Kambeitz, J, O'Carroll, C, Seal, ML, et al. Induction of psychosis by Δ9-tetrahydrocannabinol reflects modulation of prefrontal and striatal function during attentional salience processing.. Arch Gen Psychiatry 69(1) : 27 -36 2012
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  • Karlsgodt, KH, Jacobson, SC, Seal, M, Fusar-Poli, P. The relationship of developmental changes in white matter to the onset of psychosis.. Curr Pharm Des 18(4) : 422 -433 2012
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  • Martin-Santos, R, Crippa, JA, Batalla, A, Bhattacharyya, S, Atakan, Z, Borgwardt, S, Allen, P, Seal, M, Langohr, K, Farré, M, et al. Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers.. Curr Pharm Des 18(32) : 4966 -4979 2012
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  • Valli, I, Stone, J, Mechelli, A, Bhattacharyya, S, Raffin, M, Poli, PF, Allen, P, Seal, M, McGuire, P. Altered medial temporal activation in subjects with prodromal signs of psychosis related to glutamate levels. International Clinical Psychopharmacology 26(&NA;) : e118 -e119 2011
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  • Winton-Brown, TT, Allen, P, Bhattacharrya, S, Borgwardt, SJ, Fusar-Poli, P, Crippa, JA, Seal, ML, Martin-Santos, R, Ffytche, D, Zuardi, AW, et al. Erratum: Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Study. Neuropsychopharmacology 36(8) : 1778 -1778 2011
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