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Loke, P, Ng, CP, Sim, T-S.
PCR cloning, heterologous expression, and characterization of isopenicillin N synthase from Streptomyces lipmanii NRRL 3584.
Canadian Journal of Microbiology
46(2)
:
166 -170
2000
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Loke, P, Sim, T.
Site-directed mutagenesis of arginine-89 supports the role of its guanidino side-chain in substrate binding by Cephalosporium acremonium isopenicillin N synthase..
FEMS Microbiol Lett
179(2)
:
423 -429
1999
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Loke, P, Sim, TS.
Glutamine-230 influences enzyme solubility but not catalysis in Streptomyces clavuligerus isopenicillin N synthase..
FEMS Microbiol Lett
173(2)
:
439 -443
1999
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Loke, P, Sim, TS.
Analysis of glutamines in catalysis in Cephalosporium acremonium isopenicillin N synthase by site-directed mutagenesis..
Biochem Biophys Res Commun
252(2)
:
472 -475
1998
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Loke, P, Sim, TS.
Mutational evidence for the role of serine-283 in Cephalosporium acremonium isopenicillin N synthase..
FEMS Microbiol Lett
165(2)
:
353 -356
1998
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