Dr Peter Houweling is a Team leader and senior research officer in the Muscle Research group at the Murdoch Children’s Research Institute (MCRI). He completed his PhD at the University of Sydney and post-doctoral appointments at the Children’s Hospital Westmead, before moving the MCRI in 2013.
He has almost 15 years of experience in the laboratory where he is working to understand the impact of genetic variants on skeletal muscle performance in health and disease.
His Team now focuses on using stem cells to model and test new treatments for patients with genetic muscle diseases, including Duchenne muscular dystrophy (DMD), Facioscapulohumeral muscular dystrophy (FSHD) and other congenital muscular dystrophies.
Dr Peter Houweling is a Team leader and senior research officer in the Muscle Research group at the Murdoch Children’s Research Institute (MCRI). He completed his PhD at the University of Sydney and post-doctoral appointments at the Children’s...
Dr Peter Houweling is a Team leader and senior research officer in the Muscle Research group at the Murdoch Children’s Research Institute (MCRI). He completed his PhD at the University of Sydney and post-doctoral appointments at the Children’s Hospital Westmead, before moving the MCRI in 2013.
He has almost 15 years of experience in the laboratory where he is working to understand the impact of genetic variants on skeletal muscle performance in health and disease.
His Team now focuses on using stem cells to model and test new treatments for patients with genetic muscle diseases, including Duchenne muscular dystrophy (DMD), Facioscapulohumeral muscular dystrophy (FSHD) and other congenital muscular dystrophies.
Top Publications
Coles, CA, Woodcock, I, Pellicci, DG, Houweling, PJ.
A Spotlight on T Lymphocytes in Duchenne Muscular Dystrophy—Not Just a Muscle Defect.
Biomedicines
10(3)
:
535
2024
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Redwan, A, Kiriaev, L, Kueh, S, Morley, JW, Houweling, P, Perry, BD, Head, SI.
Six weeks of N-acetylcysteine antioxidant in drinking water decreases pathological fiber branching in MDX mouse dystrophic fast-twitch skeletal muscle.
Frontiers in Physiology
14:
1109587
2024
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Woodcock, IR, Tachas, G, Desem, N, Houweling, PJ, Kean, M, Emmanuel, J, Kennedy, R, Carroll, K, de Valle, K, Adams, J, et al.
A phase 2 open-label study of the safety and efficacy of weekly dosing of ATL1102 in patients with non-ambulatory Duchenne muscular dystrophy and pharmacology in mdx mice.
PLOS ONE
19(1)
:
e0294847
2024
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Haug, M, Reischl, B, Nübler, S, Kiriaev, L, Mázala, DAG, Houweling, PJ, North, KN, Friedrich, O, Head, SI.
Absence of the Z-disc protein α-actinin-3 impairs the mechanical stability of Actn3KO mouse fast-twitch muscle fibres without altering their contractile properties or twitch kinetics.
Skeletal Muscle
12(1)
:
14
2022
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Clayton, JS, Suleski, I, Vo, C, Smith, R, Scriba, CK, Saker, S, Larmonier, T, Malfatti, E, Romero, NB, Houweling, PJ, et al.
Generation of an induced pluripotent stem cell line from a 3-month-old nemaline myopathy patient with a heterozygous dominant c.515C > A (p.Ala172Glu) variant in the ACTA1 gene.
Stem Cell Research
63:
102829
2022
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