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Details

Role Team Leader / Senior Research Officer
Research area Genomic Medicine

Contact

Available for student supervision
Dr Peter Houweling is a Team leader and senior research officer in the Muscle Research group at the Murdoch Children’s Research Institute (MCRI). He completed his PhD at the University of Sydney and post-doctoral appointments at the Children’s Hospital Westmead, before moving the MCRI in 2013.

He has almost 15 years of experience in the laboratory where he is working to understand the impact of genetic variants on skeletal muscle performance in health and disease.

His Team now focuses on using stem cells to model and test new treatments for patients with genetic muscle diseases, including Duchenne muscular dystrophy (DMD), Facioscapulohumeral muscular dystrophy (FSHD) and other congenital muscular dystrophies.
Dr Peter Houweling is a Team leader and senior research officer in the Muscle Research group at the Murdoch Children’s Research Institute (MCRI). He completed his PhD at the University of Sydney and post-doctoral appointments at the Children’s...
Dr Peter Houweling is a Team leader and senior research officer in the Muscle Research group at the Murdoch Children’s Research Institute (MCRI). He completed his PhD at the University of Sydney and post-doctoral appointments at the Children’s Hospital Westmead, before moving the MCRI in 2013.

He has almost 15 years of experience in the laboratory where he is working to understand the impact of genetic variants on skeletal muscle performance in health and disease.

His Team now focuses on using stem cells to model and test new treatments for patients with genetic muscle diseases, including Duchenne muscular dystrophy (DMD), Facioscapulohumeral muscular dystrophy (FSHD) and other congenital muscular dystrophies.

Top Publications

  • Coles, CA, Woodcock, I, Pellicci, DG, Houweling, PJ. A Spotlight on T Lymphocytes in Duchenne Muscular Dystrophy—Not Just a Muscle Defect. Biomedicines 10(3) : 535 2024
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  • Redwan, A, Kiriaev, L, Kueh, S, Morley, JW, Houweling, P, Perry, BD, Head, SI. Six weeks of N-acetylcysteine antioxidant in drinking water decreases pathological fiber branching in MDX mouse dystrophic fast-twitch skeletal muscle. Frontiers in Physiology 14: 1109587 2024
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  • Woodcock, IR, Tachas, G, Desem, N, Houweling, PJ, Kean, M, Emmanuel, J, Kennedy, R, Carroll, K, de Valle, K, Adams, J, et al. A phase 2 open-label study of the safety and efficacy of weekly dosing of ATL1102 in patients with non-ambulatory Duchenne muscular dystrophy and pharmacology in mdx mice. PLOS ONE 19(1) : e0294847 2024
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  • Haug, M, Reischl, B, Nübler, S, Kiriaev, L, Mázala, DAG, Houweling, PJ, North, KN, Friedrich, O, Head, SI. Absence of the Z-disc protein α-actinin-3 impairs the mechanical stability of Actn3KO mouse fast-twitch muscle fibres without altering their contractile properties or twitch kinetics. Skeletal Muscle 12(1) : 14 2022
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  • Clayton, JS, Suleski, I, Vo, C, Smith, R, Scriba, CK, Saker, S, Larmonier, T, Malfatti, E, Romero, NB, Houweling, PJ, et al. Generation of an induced pluripotent stem cell line from a 3-month-old nemaline myopathy patient with a heterozygous dominant c.515C > A (p.Ala172Glu) variant in the ACTA1 gene. Stem Cell Research 63: 102829 2022
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