Dr Peter Houweling is a Team leader and senior research officer in the Muscle Research group at the Murdoch Children’s Research Institute (MCRI). He completed his PhD at the University of Sydney and post-doctoral appointments at the Children’s Hospital Westmead, before moving the MCRI in 2013.
He has almost 15 years of experience in the laboratory where he is working to understand the impact of genetic variants on skeletal muscle performance in health and disease.
His Team now focuses on using stem cells to model and test new treatments for patients with genetic muscle diseases, including Duchenne muscular dystrophy (DMD), Facioscapulohumeral muscular dystrophy (FSHD) and other congenital muscular dystrophies.
Dr Peter Houweling is a Team leader and senior research officer in the Muscle Research group at the Murdoch Children’s Research Institute (MCRI). He completed his PhD at the University of Sydney and post-doctoral appointments at the Children’s...
Dr Peter Houweling is a Team leader and senior research officer in the Muscle Research group at the Murdoch Children’s Research Institute (MCRI). He completed his PhD at the University of Sydney and post-doctoral appointments at the Children’s Hospital Westmead, before moving the MCRI in 2013.
He has almost 15 years of experience in the laboratory where he is working to understand the impact of genetic variants on skeletal muscle performance in health and disease.
His Team now focuses on using stem cells to model and test new treatments for patients with genetic muscle diseases, including Duchenne muscular dystrophy (DMD), Facioscapulohumeral muscular dystrophy (FSHD) and other congenital muscular dystrophies.
Top Publications
Suleski, IS, Smith, R, Vo, C, Scriba, CK, Saker, S, Larmonier, T, Malfatti, E, Romero, NB, Houweling, PJ, Nowak, KJ, et al.
Generation of two isogenic induced pluripotent stem cell lines from a 1-month-old nemaline myopathy patient harbouring a homozygous recessive c.121C > T (p.Arg39Ter) variant in the ACTA1 gene.
Stem Cell Research
63:
102830
2022
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Kiriaev, L, Houweling, PJ, North, KN, Head, SI.
Loss of α-actinin-3 confers protection from eccentric contraction damage in fast-twitch EDL muscles from aged mdx dystrophic mice by reducing pathological fibre branching.
Human Molecular Genetics
31(9)
:
ddab326
2022
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Wyckelsma, VL, Venckunas, T, Houweling, PJ, Schlittler, M, Lauschke, VM, Tiong, CF, Wood, HD, Paulauskas, H, Eimantas, N, Andersson, DC, et al.
Response to Mörseburg et al..
American Journal of Human Genetics
109(5)
:
973
2022
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Kiriaev, L, Kueh, S, Morley, JW, Houweling, PJ, Chan, S, North, KN, Head, SI.
Dystrophin-negative slow-twitch soleus muscles are not susceptible to eccentric contraction induced injury over the lifespan of the mdx mouse.
American Journal of Physiology - Cell Physiology
321(4)
:
c704 -c720
2021
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Seto, JT, Roeszler, KN, Meehan, LR, Wood, HD, Tiong, C, Bek, L, Lee, SF, Shah, M, Quinlan, KGR, Gregorevic, P, et al.
ACTN3 genotype influences skeletal muscle mass regulation and response to dexamethasone.
Science Advances
7(27)
:
2021
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