Dr Ruili Li (BS, MS, Ph.D) is a senior research fellow at the Surgical Research group, Murdoch Children's Research Institute, Honorary research fellow at the Paediatric Department of Melbourne University, Australia.
Dr Li started her research in reproductive biology when she did her Master's degree at Beijing Agricultural University on cryopreservation of rabbit embryos. She then came to Australia and completed her Ph.D in cryopreservation of mouse, goat and sheep embryos and embryonic cell development on the attempt to isolate embryonic stem cells under the supervision of Prof. Alan Trounson and Prof. Euan Roberts.
Dr Li joined Prof Richard Harvey's lab at the Water and Eliza Hall Institute after her Ph.D completion and focused on the establishment of the gene knockout system using embryonic stem cells followed by many years' experience of generating and analysis of genetically modified mice. She gained lots of experience on molecular biology, developmental biology and haematology while she was working side-by-side with many experts there.
Dr Li joined Prof Andrew Sinclair's Lab at Murdoch Children’s Research Institute and studied germ cell development during sex determination with focus on the regulation of pluripotency and differentiation in early germ cells, which involved in generating transgenic mice with inducible gene expression (TCCre, TCGFP, MkxHA mice) using ES cells and tetraploid embryos as well as blastocyst injection. With Prof Sinclair and MCRI executive committee's support, Dr Li involved in the establishment of MCRI facility of the transgenic and embryo service by drafting the business plan and was subsequently appointed as the manager of the facility during 2009-2010.
Dr Li joined Prof John Hutson's group in 2010 and has been working on the research in undescended testis at the Surgical Research group at Murdoch Children’s Research Institute. Currently Dr Li leads the laboratory research on testis descent and gonocyte transformation into spermatogonial stem cells using various transgenic, gene-knockout and naturally mutated rodent models as well as human biopsies of undescended testis (UDT). The research focuses on understanding the cellular and molecular regulation of postnatal germ cell development aiming to prevent the problems related to undescended testis (UDT), which are infertility and testicular cancer in young adult men with a history of UDT.
Dr Ruili Li (BS, MS, Ph.D) is a senior research fellow at the Surgical Research group, Murdoch Children's Research Institute, Honorary research fellow at the Paediatric Department of Melbourne University, Australia.
Dr Li started her research in...
Dr Ruili Li (BS, MS, Ph.D) is a senior research fellow at the Surgical Research group, Murdoch Children's Research Institute, Honorary research fellow at the Paediatric Department of Melbourne University, Australia.
Dr Li started her research in reproductive biology when she did her Master's degree at Beijing Agricultural University on cryopreservation of rabbit embryos. She then came to Australia and completed her Ph.D in cryopreservation of mouse, goat and sheep embryos and embryonic cell development on the attempt to isolate embryonic stem cells under the supervision of Prof. Alan Trounson and Prof. Euan Roberts.
Dr Li joined Prof Richard Harvey's lab at the Water and Eliza Hall Institute after her Ph.D completion and focused on the establishment of the gene knockout system using embryonic stem cells followed by many years' experience of generating and analysis of genetically modified mice. She gained lots of experience on molecular biology, developmental biology and haematology while she was working side-by-side with many experts there.
Dr Li joined Prof Andrew Sinclair's Lab at Murdoch Children’s Research Institute and studied germ cell development during sex determination with focus on the regulation of pluripotency and differentiation in early germ cells, which involved in generating transgenic mice with inducible gene expression (TCCre, TCGFP, MkxHA mice) using ES cells and tetraploid embryos as well as blastocyst injection. With Prof Sinclair and MCRI executive committee's support, Dr Li involved in the establishment of MCRI facility of the transgenic and embryo service by drafting the business plan and was subsequently appointed as the manager of the facility during 2009-2010.
Dr Li joined Prof John Hutson's group in 2010 and has been working on the research in undescended testis at the Surgical Research group at Murdoch Children’s Research Institute. Currently Dr Li leads the laboratory research on testis descent and gonocyte transformation into spermatogonial stem cells using various transgenic, gene-knockout and naturally mutated rodent models as well as human biopsies of undescended testis (UDT). The research focuses on understanding the cellular and molecular regulation of postnatal germ cell development aiming to prevent the problems related to undescended testis (UDT), which are infertility and testicular cancer in young adult men with a history of UDT.
Top Publications
Hart, AH, Hartley, L, Sourris, K, Stadler, ES, Li, R, Stanley, EG, Tam, PPL, Elefanty, AG, Robb, L.
Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo..
Development
129(15)
:
3597 -3608
2002
view publication
Tarrant, JM, Groom, J, Metcalf, D, Li, R, Borobokas, B, Wright, MD, Tarlinton, D, Robb, L.
The absence of Tssc6, a member of the tetraspanin superfamily, does not affect lymphoid development but enhances in vitro T-cell proliferative responses..
Mol Cell Biol
22(14)
:
5006 -5018
2002
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Robb, L, Dimitriadis, E, Li, R, Salamonsen, LA.
Leukemia inhibitory factor and interleukin-11: cytokines with key roles in implantation..
J Reprod Immunol
57(1-2)
:
129 -141
2002
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Robb, L, Tarrant, J, Groom, J, Ibrahim, M, Li, R, Borobakas, B, Wright, MD.
Molecular characterisation of mouse and human TSSC6: evidence that TSSC6 is a genuine member of the tetraspanin superfamily and is expressed specifically in haematopoietic organs..
Biochim Biophys Acta
1522(1)
:
31 -41
2001
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Li, R, Hartley, L, Robb, L.
Cloning of rat interleukin 11 and interleukin 11 receptor alpha chain and analysis of their expression in rat uterus in the peri-implantation period..
Reproduction
122(4)
:
593 -600
2001
view publication