Assoc/Prof. Salvatore Pepe is a clinical scientist who leads the Molecular & Cellular Cardiology Laboratory in the Heart Research Group (Clinical Sciences Theme) at the Murdoch Children's Research Institute (MCRI) and is a clinical research manager in the Department of Cardiology, Royal Children's Hospital.
Before working at Melbourne Children's Campus, he was Head of the Cardiothoracic Surgical Research Laboratory, (Department of Cardiothoracic Surgery), at the Alfred Hospital, and Adjunct Senior Lecturer, Department of Surgery -Alfred, Central Clinical School, Monash University, involved in clinical trial and laboratory research focused on cellular and mitochondrial processes in heart failure, transplantation, and cardiopulmonary bypass surgery. Earlier posts include a Research Fellowship at the Baker Heart Research Institute, Melbourne, and a National Institutes of Health Fogarty Postdoctoral Fellowship at the Gerontology Research Center, (LCS, IRP, NIA, NIH) Johns Hopkins Hospital, Bayview Campus, Baltimore, USA.
Working with cardiac surgery, cardiology and intensive care clinicians, Dr Pepe's work is focused on complications arising from congenital and acquired heart and lung disorders, premature birth and surgical interventions. His research program spans from in vitro and in vivo laboratory studies to clinical trials, translating new understanding of disease mechanisms and novel therapy to clinical use. Currently he is Chief Investigator A of an NHMRC funded clinical trial, testing the safety and efficacy of cord blood stem cell therapy in children at risk of heart failure.
A/Prof Pepe is Deputy Editor-in-Chief of Australia's premiere cardiology research journal, Heart Lung & Circulation (Elsevier, Sydney), and is also an Associate Editor for Heliyon-Clinical Research (Cell Press-Elsevier, London UK), and Frontiers in Cardiovascular Medicine -Cardiovascular Biologics & Regenerative Medicine (Lausanne, Switzerland). A/Prof Pepe has regularly served NHMRC, NHF and ARC as a grant funding panel member and external expert grant reviewer and is an invited peer reviewer for numerous medical and scientific journals. He is Past-President of the International Society for Heart Research and recipient of the 2016 ISHR Distinguished Leader Award. He is an international Fellow of the American Heart Association and a Fellow of the Cardiac Society of Australia and New Zealand.
Assoc/Prof. Salvatore Pepe is a clinical scientist who leads the Molecular & Cellular Cardiology Laboratory in the Heart Research Group (Clinical Sciences Theme) at the Murdoch Children's Research Institute (MCRI) and is a clinical research manager in...
Assoc/Prof. Salvatore Pepe is a clinical scientist who leads the Molecular & Cellular Cardiology Laboratory in the Heart Research Group (Clinical Sciences Theme) at the Murdoch Children's Research Institute (MCRI) and is a clinical research manager in the Department of Cardiology, Royal Children's Hospital.
Before working at Melbourne Children's Campus, he was Head of the Cardiothoracic Surgical Research Laboratory, (Department of Cardiothoracic Surgery), at the Alfred Hospital, and Adjunct Senior Lecturer, Department of Surgery -Alfred, Central Clinical School, Monash University, involved in clinical trial and laboratory research focused on cellular and mitochondrial processes in heart failure, transplantation, and cardiopulmonary bypass surgery. Earlier posts include a Research Fellowship at the Baker Heart Research Institute, Melbourne, and a National Institutes of Health Fogarty Postdoctoral Fellowship at the Gerontology Research Center, (LCS, IRP, NIA, NIH) Johns Hopkins Hospital, Bayview Campus, Baltimore, USA.
Working with cardiac surgery, cardiology and intensive care clinicians, Dr Pepe's work is focused on complications arising from congenital and acquired heart and lung disorders, premature birth and surgical interventions. His research program spans from in vitro and in vivo laboratory studies to clinical trials, translating new understanding of disease mechanisms and novel therapy to clinical use. Currently he is Chief Investigator A of an NHMRC funded clinical trial, testing the safety and efficacy of cord blood stem cell therapy in children at risk of heart failure.
A/Prof Pepe is Deputy Editor-in-Chief of Australia's premiere cardiology research journal, Heart Lung & Circulation (Elsevier, Sydney), and is also an Associate Editor for Heliyon-Clinical Research (Cell Press-Elsevier, London UK), and Frontiers in Cardiovascular Medicine -Cardiovascular Biologics & Regenerative Medicine (Lausanne, Switzerland). A/Prof Pepe has regularly served NHMRC, NHF and ARC as a grant funding panel member and external expert grant reviewer and is an invited peer reviewer for numerous medical and scientific journals. He is Past-President of the International Society for Heart Research and recipient of the 2016 ISHR Distinguished Leader Award. He is an international Fellow of the American Heart Association and a Fellow of the Cardiac Society of Australia and New Zealand.
Top Publications
Pepe, S, McLennan, PL.
(n-3) Long Chain PUFA Dose-Dependently Increase Oxygen Utilization Efficiency and Inhibit Arrhythmias after Saturated Fat Feeding in Rats 1.
Journal of Nutrition
137(11)
:
2377 -2383
2007
view publication
Pepe, S.
Dietary Polyunsaturated Fatty Acids and Age‐Related Membrane Changes in the Heart.
Annals of the New York Academy of Sciences
1114(1)
:
381 -388
2007
view publication
Pepe, S, Delbridge, LMD.
Pacemaker Cell and Atrial Function: Unravelling How Calcium Initiates and Regulates the Heart Beat and How Ionic Dysfunction, ‘Channelopathies’ and Other Membrane Remodelling Contribute to Atrial Fibrillation.
Heart Lung and Circulation
16(5)
:
331 -334
2007
view publication
Lim, H-K, Anderson, J, Leong, J-Y, Pepe, S, Salamonsen, RF, Rosenfeldt, FL.
What is the Role of Leukocyte Depletion in Cardiac Surgery?.
Heart Lung and Circulation
16(4)
:
243 -253
2007
view publication
Kaye, DM, Preovolos, A, Marshall, T, Byrne, M, Hoshijima, M, Hajjar, R, Mariani, JA, Pepe, S, Chien, KR, Power, JM.
Percutaneous Cardiac Recirculation-Mediated Gene Transfer of an Inhibitory Phospholamban Peptide Reverses Advanced Heart Failure in Large Animals.
Journal of the American College of Cardiology
50(3)
:
253 -260
2007
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