Details

Role Scientific Lead

Group iPSC Derivation & Gene Editing Facility

Top Publications

Kao, T, Labonne, T, Niclis, JC, Chaurasia, R, Lokmic, Z, Qian, E, Bruveris, FF, Howden, SE, Motazedian, A, Schiesser, JV, et al. GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives.. Stem Cell Reports 7(3) : 518 -526 2016
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Howden, SE, McColl, B, Glaser, A, Vadolas, J, Petrou, S, Little, MH, Elefanty, AG, Stanley, EG. A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells.. Stem Cell Reports 7(3) : 508 -517 2016
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Phelan, DG, Anderson, DJ, Howden, SE, Wong, RCB, Hickey, PF, Pope, K, Wilson, GR, Pébay, A, Davis, AM, Petrou, S, et al. ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.. Eur Heart J 37(33) : 2586 -2590 2016
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Howden, SE, Maufort, JP, Duffin, BM, Elefanty, AG, Stanley, EG, Thomson, JA. Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts.. Stem Cell Reports 5(6) : 1109 -1118 2015
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McColl, B, Howden, S, Vadolas, J. Site-specific integration of bacterial artificial chromosomes into human cells.. Methods Mol Biol 1227: 309 -321 2015
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