Details

Role Scientific Lead

Group iPSC Derivation & Gene Editing Facility

Top Publications

Chen, G, Gulbranson, DR, Hou, Z, Bolin, JM, Ruotti, V, Probasco, MD, Smuga-Otto, K, Howden, SE, Diol, NR, Propson, NE, et al. Chemically defined conditions for human iPSC derivation and culture.. Nat Methods 8(5) : 424 -429 2011
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Howden, SE, Gore, A, Li, Z, Fung, H-L, Nisler, BS, Nie, J, Chen, G, McIntosh, BE, Gulbranson, DR, Diol, NR, et al. Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy.. Proc Natl Acad Sci U S A 108(16) : 6537 -6542 2011
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Zaibak, F, Kozlovski, J, Vadolas, J, Sarsero, JP, Williamson, R, Howden, SE. Integration of functional bacterial artificial chromosomes into human cord blood-derived multipotent stem cells.. Gene Ther 16(3) : 404 -414 2009
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Howden, SE, Voullaire, L, Wardan, H, Williamson, R, Vadolas, J. Site-specific, Rep-mediated integration of the intact beta-globin locus in the human erythroleukaemic cell line K562.. Gene Ther 15(20) : 1372 -1383 2008
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Howden, SE, Voullaire, L, Ioannou, P, Williamson, R, Vadalos, J. Transient expression of AAV rep protein facilitates targeted integration of a 200 kb BAC containing the entire beta-globin locus. Blood Cells Molecules and Diseases 40(2) : 288 2008
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