photo of

Details

Role Princ Res Fellow, Lead, Bone & Cartilage
Research area Stem Cell Medicine
Group Blood Development

Contact

Phone show phone number
Available for student supervision
Human skeletal development and correct bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research aims to understand the molecular basis of these disorders to improve diagnosis and genetic counselling, identify new therapeutic targets and test new treatments to ultimately improve the quality of life for children with these debilitating conditions
Human skeletal development and correct bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s...
Human skeletal development and correct bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research aims to understand the molecular basis of these disorders to improve diagnosis and genetic counselling, identify new therapeutic targets and test new treatments to ultimately improve the quality of life for children with these debilitating conditions

Top Publications

  • Risteli, M, Ruotsalainen, H, Salo, AM, Sormunen, R, Sipilä, L, Baker, NL, Lamandé, SR, Vimpari-Kauppinen, L, Myllylä, R. Reduction of Lysyl Hydroxylase 3 Causes Deleterious Changes in the Deposition and Organization of Extracellular Matrix*. Journal of Biological Chemistry 284(41) : 28204 -28211 2009
    view publication
  • Ishida, Y, Yamamoto, A, Kitamura, A, Lamandé, SR, Yoshimori, T, Bateman, JF, Kubota, H, Nagata, K. Autophagic Elimination of Misfolded Procollagen Aggregates in the Endoplasmic Reticulum as a Means of Cell Protection. Molecular Biology of the Cell 20(11) : 2744 -2754 2009
    view publication
  • Allen, JM, Zamurs, L, Brachvogel, B, Schlötzer-Schrehardt, U, Hansen, U, Lamandé, SR, Rowley, L, Fitzgerald, J, Bateman, JF. Mice Lacking the Extracellular Matrix Protein WARP Develop Normally but Have Compromised Peripheral Nerve Structure and Function*. Journal of Biological Chemistry 284(18) : 12020 -12030 2009
    view publication
  • Bateman, JF, Boot-Handford, RP, Lamandé, SR. Genetic diseases of connective tissues: cellular and extracellular effects of ECM mutations. Nature Reviews Genetics 10(3) : 173 -183 2009
    view publication
  • Baker, NL, Zamurs, L, Tooley, L, Peat, RA, North, KN, Lamande, SR. An a2(VI) C1 mutation prevents collagen VI microfibril formation. Matrix Biology 27: 54 2008
    view publication

Page 12 of 22

Related links