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Details

Role Research Officer
Research area Genomic Medicine

Contact

Available for student supervision
Dr Svenja Pachernegg is a postdoctoral researcher in the Reproductive Development Group at the Murdoch Children's Research Institute in Melbourne. Svenja’s research interests are pluripotent stem cell biology, developmental biology, and disease modelling. She completed her PhD in Neuroscience in Germany in 2014, working on glutamate receptor function in mouse embryonic and neural stem cells. Svenja is now applying her stem cell and molecular biology skills to a differentiation protocol for human gonadal organoids to model Disorders of Sex Development.
Dr Svenja Pachernegg is a postdoctoral researcher in the Reproductive Development Group at the Murdoch Children's Research Institute in Melbourne. Svenja’s research interests are pluripotent stem cell biology, developmental biology, and disease...
Dr Svenja Pachernegg is a postdoctoral researcher in the Reproductive Development Group at the Murdoch Children's Research Institute in Melbourne. Svenja’s research interests are pluripotent stem cell biology, developmental biology, and disease modelling. She completed her PhD in Neuroscience in Germany in 2014, working on glutamate receptor function in mouse embryonic and neural stem cells. Svenja is now applying her stem cell and molecular biology skills to a differentiation protocol for human gonadal organoids to model Disorders of Sex Development.

Top Publications

  • Pachernegg, S, Eilebrecht, S, Eilebrecht, E, Schöneborn, H, Neumann, S, Benecke, AG, Hollmann, M. The siRNA-mediated knockdown of GluN3A in 46C-derived neural stem cells affects mRNA expression levels of neural genes, including known iGluR interactors.. PLoS One 13(2) : e0192242 2018
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  • Pachernegg, S, Münster, Y, Muth-Köhne, E, Fuhrmann, G, Hollmann, M. GluA2 is rapidly edited at the Q/R site during neural differentiation in vitro.. Front Cell Neurosci 9: 69 2015
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  • Pachernegg, S, Joshi, I, Muth-Köhne, E, Pahl, S, Münster, Y, Terhag, J, Karus, M, Werner, M, Ma-Högemeier, Z-L, Körber, C, et al. Undifferentiated embryonic stem cells express ionotropic glutamate receptor mRNAs.. Front Cell Neurosci 7: 241 2013
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  • Pachernegg, S, Strutz-Seebohm, N, Hollmann, M. GluN3 subunit-containing NMDA receptors: not just one-trick ponies.. Trends Neurosci 35(4) : 240 -249 2012
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  • Muth-Köhne, E, Pachernegg, S, Karus, M, Faissner, A, Hollmann, M. Expression of NMDA receptors and Ca2+-impermeable AMPA receptors requires neuronal differentiation and allows discrimination between two different types of neural stem cells.. Cell Physiol Biochem 26(6) : 935 -946 2010
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