Associate Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation for Stem Cell Medicine (reNEW). David co-directs, with Associate Professor Rachel Conyers, the Australian Cardio-Oncology Registry (ACOR), a national program targeted at improving long-term cardiac health outcomes for childhood cancer survivors. The focus of Associate Professor Elliott’s laboratory is to develop pluripotent stem cell-based models of heart disease and use these models to find new therapies for heart disease. Throughout his career Assoc. Prof. Elliott has made important contributions to understanding the molecular control of heart muscle development, function and disease.
Associate Professor David Elliott completed his PhD on the genetics of heart development at The Victor Chang Cardiac Research Institute and The Walter and Eliza Hall Institute. He continued to post-doctoral studies at the University of Cambridge studying the nervous system in the fruit fly at the Wellcome Trust/Cancer Research UK Gurdon Institute. Associate Professor Elliott began using human pluripotent stem cells in a second post-doc with Professors Andrew Elefanty and Ed Stanley at Monash University where he generated key stem cell lines and identified the first cardiac lineage cell surface markers.
Associate Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation for Stem Cell Medicine (reNEW). David co-directs, with Associate...
Associate Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation for Stem Cell Medicine (reNEW). David co-directs, with Associate Professor Rachel Conyers, the Australian Cardio-Oncology Registry (ACOR), a national program targeted at improving long-term cardiac health outcomes for childhood cancer survivors. The focus of Associate Professor Elliott’s laboratory is to develop pluripotent stem cell-based models of heart disease and use these models to find new therapies for heart disease. Throughout his career Assoc. Prof. Elliott has made important contributions to understanding the molecular control of heart muscle development, function and disease.
Associate Professor David Elliott completed his PhD on the genetics of heart development at The Victor Chang Cardiac Research Institute and The Walter and Eliza Hall Institute. He continued to post-doctoral studies at the University of Cambridge studying the nervous system in the fruit fly at the Wellcome Trust/Cancer Research UK Gurdon Institute. Associate Professor Elliott began using human pluripotent stem cells in a second post-doc with Professors Andrew Elefanty and Ed Stanley at Monash University where he generated key stem cell lines and identified the first cardiac lineage cell surface markers.
Top Publications
Park, S, Kim, H, Lee, S, Kim, J, Jung, T, Choi, SW, Park, B, Kang, S, Elliott, DA, Stanley, EG, et al.
Effect and application of cryopreserved three‐dimensional microcardiac spheroids in myocardial infarction therapy.
Clinical and Translational Medicine
12(1)
:
e721
2022
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McNamara, J, Parker, B, Voges, H, Mehdiabadi, N, Bolk, F, Chung, J, Charitakis, N, Molendijk, J, Lal, S, Ramialison, M, et al.
Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle.
2022
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Charitakis, N, Salim, A, Piers, A, Watt, K, Porrello, E, Elliott, D, Ramialison, M.
Disparities in spatially variable gene calling highlight the need for benchmarking spatial transcriptomics methods.
2022
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Lopes, LR, Hernandez, SG, Lorenzini, M, Futema, M, Chumakova, O, Villacorta, E, Garcia-Pavia, P, Bilbao, R, Sandin-Fuentes, M, Pinilla, JG, et al.
Alpha-protein kinase 3 (ALPK3) truncating variants cause an autosomal dominant form of hypertrophic cardiomyopathy.
European Heart Journal
42(Supplement_1)
:
ehab724.1781
2021
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Lopes, LR, Garcia-Hernández, S, Lorenzini, M, Futema, M, Chumakova, O, Zateyshchikov, D, Isidoro-Garcia, M, Villacorta, E, Escobar-Lopez, L, Garcia-Pavia, P, et al.
Alpha-protein kinase 3 (ALPK3)-truncating variants are a cause of autosomal dominant hypertrophic cardiomyopathy.
European Heart Journal
42(32)
:
ehab424
2021
view publication