Associate Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation for Stem Cell Medicine (reNEW). David co-directs, with Associate Professor Rachel Conyers, the Australian Cardio-Oncology Registry (ACOR), a national program targeted at improving long-term cardiac health outcomes for childhood cancer survivors. The focus of Associate Professor Elliott’s laboratory is to develop pluripotent stem cell-based models of heart disease and use these models to find new therapies for heart disease. Throughout his career Assoc. Prof. Elliott has made important contributions to understanding the molecular control of heart muscle development, function and disease.
Associate Professor David Elliott completed his PhD on the genetics of heart development at The Victor Chang Cardiac Research Institute and The Walter and Eliza Hall Institute. He continued to post-doctoral studies at the University of Cambridge studying the nervous system in the fruit fly at the Wellcome Trust/Cancer Research UK Gurdon Institute. Associate Professor Elliott began using human pluripotent stem cells in a second post-doc with Professors Andrew Elefanty and Ed Stanley at Monash University where he generated key stem cell lines and identified the first cardiac lineage cell surface markers.
Associate Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation for Stem Cell Medicine (reNEW). David co-directs, with Associate...
Associate Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation for Stem Cell Medicine (reNEW). David co-directs, with Associate Professor Rachel Conyers, the Australian Cardio-Oncology Registry (ACOR), a national program targeted at improving long-term cardiac health outcomes for childhood cancer survivors. The focus of Associate Professor Elliott’s laboratory is to develop pluripotent stem cell-based models of heart disease and use these models to find new therapies for heart disease. Throughout his career Assoc. Prof. Elliott has made important contributions to understanding the molecular control of heart muscle development, function and disease.
Associate Professor David Elliott completed his PhD on the genetics of heart development at The Victor Chang Cardiac Research Institute and The Walter and Eliza Hall Institute. He continued to post-doctoral studies at the University of Cambridge studying the nervous system in the fruit fly at the Wellcome Trust/Cancer Research UK Gurdon Institute. Associate Professor Elliott began using human pluripotent stem cells in a second post-doc with Professors Andrew Elefanty and Ed Stanley at Monash University where he generated key stem cell lines and identified the first cardiac lineage cell surface markers.
Top Publications
Voges, HK, Mills, RJ, Elliott, DA, Parton, RG, Porrello, ER, Hudson, JE.
Development of a human cardiac organoid injury model reveals innate regenerative potential..
Development
144(6)
:
1118 -1127
2017
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Ng, ES, Azzola, L, Bruveris, FF, Calvanese, V, Phipson, B, Vlahos, K, Hirst, C, Jokubaitis, VJ, Yu, QC, Maksimovic, J, et al.
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros..
Nat Biotechnol
34(11)
:
1168 -1179
2016
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Kao, T, Labonne, T, Niclis, JC, Chaurasia, R, Lokmic, Z, Qian, E, Bruveris, FF, Howden, SE, Motazedian, A, Schiesser, JV, et al.
GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives..
Stem Cell Reports
7(3)
:
518 -526
2016
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Phelan, DG, Anderson, DJ, Howden, SE, Wong, RCB, Hickey, PF, Pope, K, Wilson, GR, Pébay, A, Davis, AM, Petrou, S, et al.
ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy..
Eur Heart J
37(33)
:
2586 -2590
2016
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Skelton, RJP, Brady, B, Khoja, S, Sahoo, D, Engel, J, Arasaratnam, D, Saleh, KK, Abilez, OJ, Zhao, P, Stanley, EG, et al.
CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells..
Stem Cell Reports
6(1)
:
95 -108
2016
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