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Details

Role Theme Director - Stem Cell Medicine
Research area Stem Cell Medicine

Contact

Available for student supervision
Professor Porrello is the Theme Director of Stem Cell Medicine and Head of the Heart Regeneration group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Professor Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Throughout his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Professor Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at the University of Melbourne, Professor Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Professor Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Medicine and Head of the Heart Regeneration group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Medicine and Head of the Heart Regeneration group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Professor Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Throughout his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Professor Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at the University of Melbourne, Professor Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Professor Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.

Top Publications

  • Batho, CAP, Reid, JD, Robinson, HR, Szappanos, HC, Devilée, LAC, Hoyte, SM, Johnston, RL, Ziegman, R, Hassan, S, Soday, L, et al. Prenylation controls proliferation in human pluripotent stem cell-derived cardiomyocytes. 2024
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  • Chiang, IK, Humphrey, D, Mills, RJ, Kaltzis, P, Pachauri, S, Graus, M, Saha, D, Wu, Z, Young, P, Sim, CB, et al. Sox7-positive endothelial progenitors establish coronary arteries and govern ventricular compaction.. EMBO Rep 24(10) : e55043 2023
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  • Charitakis, N, Salim, A, Piers, AT, Watt, KI, Porrello, ER, Elliott, DA, Ramialison, M. Disparities in spatially variable gene calling highlight the need for benchmarking spatial transcriptomics methods.. Genome Biol 24(1) : 209 2023
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  • Voges, HK, Mills, RJ, Porrello, ER, Hudson, JE. Generation of vascularized human cardiac organoids for 3D in vitro modeling.. STAR Protoc 4(3) : 102371 2023
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  • Ter Huurne, M, Parker, BL, Liu, NQ, Qian, EL, Vivien, C, Karavendzas, K, Mills, RJ, Saville, JT, Abu-Bonsrah, D, Wise, AF, et al. GLA-modified RNA treatment lowers GB3 levels in iPSC-derived cardiomyocytes from Fabry-affected individuals.. Am J Hum Genet 110(9) : 1600 -1605 2023
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