Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Top Publications
Hallab, JC, Nim, HT, Stolper, J, Chahal, G, Waylen, L, Bolk, F, Elliott, DA, Porrello, E, Ramialison, M.
Towards spatio-temporally resolved developmental cardiac gene regulatory networks in zebrafish.
Briefings in Functional Genomics
20(6)
:
427 -433
2021
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Zhuang, A, Calkin, AC, Lau, S, Kiriazis, H, Donner, DG, Liu, Y, Bond, ST, Moody, SC, Gould, EAM, Colgan, TD, et al.
Loss of the long non-coding RNA OIP5-AS1 exacerbates heart failure in a sex-specific manner.
iScience
24(6)
:
102537
2021
view publication
McNamara, JW, Porrello, ER.
From Fragrances to Heart Regeneration.
Circulation
143(20)
:
1987 -1990
2021
view publication
Watt, KI, Henstridge, DC, Ziemann, M, Sim, CB, Montgomery, MK, Samocha-Bonet, D, Parker, BL, Dodd, GT, Bond, ST, Salmi, TM, et al.
Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease..
Nat Commun
12(1)
:
2887
2021
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Mills, RJ, Humphrey, SJ, Fortuna, PRJ, Lor, M, Foster, SR, Quaife-Ryan, GA, Johnston, RL, Dumenil, T, Bishop, C, Rudraraju, R, et al.
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection.
Cell
184(8)
:
2167 -2182.e22
2021
view publication