photo of

Details

Role Theme Director - Stem Cell Biology
Research area Stem Cell Medicine

Contact

Available for student supervision
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.

Top Publications

  • McOwan, TN, Craig, LA, Tripdayonis, A, Karavendzas, K, Cheung, MM, Porrello, ER, Conyers, R, Elliott, DA. Evaluating anthracycline cardiotoxicity associated single nucleotide polymorphisms in a paediatric cohort with early onset cardiomyopathy. Cardio-Oncology 6(1) : 5 2020
    view publication
  • Quaife-Ryan, GA, Mills, RJ, Lavers, G, Voges, HK, Vivien, CJ, Elliott, DA, Ramialison, M, Hudson, JE, Porrello, ER. β-Catenin drives distinct transcriptional networks in proliferative and nonproliferative cardiomyocytes. Development 147(22) : dev193417 2020
    view publication
  • Nalliah, CJ, Bell, JR, Raaijmakers, AJA, Waddell, HM, Wells, SP, Bernasochi, GB, Montgomery, MK, Binny, S, Watts, T, Joshi, SB, et al. Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality. Journal of the American College of Cardiology 76(10) : 1197 -1211 2020
    view publication
  • Nagareddy, PR, Sreejit, G, Lee, MK, Athmanathan, B, Quaife-Ryan, GA, Abdel-Latif, A, Porrello, ER, Murphy, A. Abstract 228: Inflammasome-Primed Neutrophils Return to the Bone Marrow to Stimulate Leukocytosis Following Myocardial Infarction. Circulation Research 127(Suppl_1) : 2020
    view publication
  • Loh, Z, Simpson, J, Ullah, A, Zhang, V, Gan, WJ, Lynch, JP, Werder, RB, Sikder, AA, Lane, K, Sim, CB, et al. HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling.. PLoS Pathog 16(7) : e1008651 2020
    view publication

Page 8 of 25