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Details

Role Theme Director - Stem Cell Biology
Research area Stem Cell Medicine

Contact

Available for student supervision
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.

Top Publications

  • Konstantinov, IE, Fricke, TA, Ivanov, Y, Porrello, E. Commentary: From bioprosthetic tissue degeneration to regeneration: A new surgical horizon in the era of regenerative medicine. Journal of Thoracic and Cardiovascular Surgery 158(3) : 742 -743 2019
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  • Wilson, CH, Bywater, MJ, Burkhart, DL, Sabò, A, Straube, J, Pendino, V, Hudson, JE, Quaife-Ryan, GA, Porrello, ER, Kress, TR, et al. Abstract 108: Reactivation of Myc Transcription in the Heart Unlocks its Proliferative Capacity. Circulation Research 125(Suppl_1) : 2019
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  • Nagareddy, P, Sreejit, G, Abdel-Latif, A, Athmanathan, B, Annabathula, R, Dhyani, A, Noothi, S, Quaife-Ryan, G, Hudson, J, Smyth, S, et al. Nlrp3 Inflammasome-Primed Neutrophils Return To The Bone Marrow To Propagate Granulopoiesis Following Myocardial Injury. Atherosclerosis 287: e22 2019
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  • Mills, RJ, Parker, BL, Monnot, P, Needham, EJ, Vivien, CJ, Ferguson, C, Parton, RG, James, DE, Porrello, ER, Hudson, JE. Development of a human skeletal micro muscle platform with pacing capabilities. Biomaterials 198: 217 -227 2019
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  • Vivien, CJ, Pichol-Thievend, C, Sim, CB, Smith, JB, Bower, NI, Hogan, BM, Hudson, JE, Francois, M, Porrello, ER. Vegfc/d-dependent regulation of the lymphatic vasculature during cardiac regeneration is influenced by injury context.. NPJ Regen Med 4: 18 2019
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