Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Top Publications
Sadek, HA, Porrello, ER.
Neonatal heart regeneration: Moving from phenomenology to regenerative medicine.
Journal of Thoracic and Cardiovascular Surgery
159(6)
:
2451 -2455
2020
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Sreejit, G, Abdel-Latif, A, Athmanathan, B, Annabathula, R, Dhyani, A, Noothi, SK, Quaife-Ryan, GA, Al-Sharea, A, Pernes, G, Dragoljevic, D, et al.
Neutrophil-Derived S100A8/A9 Amplify Granulopoiesis After Myocardial Infarction.
Circulation
141(13)
:
1080 -1094
2020
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Lock, MC, Tellam, RL, Darby, JRT, Soo, JY, Brooks, DA, Macgowan, CK, Selvanayagam, JB, Porrello, ER, Seed, M, Keller-Wood, M, et al.
Differential gene responses 3 days following infarction in the fetal and adolescent sheep heart.
Physiological Genomics
52(3)
:
143 -159
2020
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Mills, RJ, Humphrey, S, Fortuna, PR, Quaife-Ryan, G, Lor, M, Ruraraju, R, Rawle, D, Le, T, Zhao, W, Lee, L, et al.
Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection.
2020
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Wells, SP, Waddell, HM, Sim, CB, Lim, SY, Bernasochi, GB, Pavlovic, D, Kirchhof, P, Porrello, ER, Delbridge, LMD, Bell, JR.
Cardiomyocyte functional screening: interrogating comparative electrophysiology of high-throughput model cell systems.
American Journal of Physiology - Cell Physiology
317(6)
:
c1256 -c1267
2019
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