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Details

Role Theme Director - Stem Cell Medicine
Research area Stem Cell Medicine

Contact

Available for student supervision
Professor Porrello is the Theme Director of Stem Cell Medicine and Head of the Heart Regeneration group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Professor Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Throughout his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Professor Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at the University of Melbourne, Professor Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Professor Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Medicine and Head of the Heart Regeneration group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Medicine and Head of the Heart Regeneration group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Professor Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Throughout his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Professor Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at the University of Melbourne, Professor Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Professor Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.

Top Publications

  • Ryan, Q-G, Ma, Z, Sim, C, Ramialison, M, Thomas, W, Hudson, J, Porrello, E. Cellular Transcriptomic Analysis of Multiple Cardiac Lineages During Heart Development and Regeneration. Heart Lung and Circulation 25: s36 2016
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  • Ma, Z, Quaife-Ryan, G, Lynch, J, McLellan, C, Mills, R, Phipps, S, Cooper-White, J, Hudson, J, Porrello, E. Intramyocardial Delivery of miR-29a Improves Cardiac Function and Prevents Pathological Remodelling Following Myocardial Infarction. Heart Lung and Circulation 25: s79 2016
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  • Lock, M, Tellam, R, Porrello, E, Soo, J, Darby, J, Brooks, D, Morrison, J. miR-133a and Target Gene Expression in the Foetus and 6 Month Old Sheep Heart in Response to Myocardial Infarction. Heart Lung and Circulation 25: s117 2016
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  • Titmarsh, DM, Glass, NR, Mills, RJ, Hidalgo, A, Wolvetang, EJ, Porrello, ER, Hudson, JE, Cooper-White, JJ. Induction of Human iPSC-Derived Cardiomyocyte Proliferation Revealed by Combinatorial Screening in High Density Microbioreactor Arrays.. Sci Rep 6: 24637 2016
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  • Vivien, CJ, Hudson, JE, Porrello, ER. Evolution, comparative biology and ontogeny of vertebrate heart regeneration.. NPJ Regen Med 1: 16012 2016
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