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Details

Role Theme Director - Stem Cell Biology
Research area Stem Cell Medicine

Contact

Available for student supervision
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.

After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.

Top Publications

  • Vivien, CJ, Hudson, JE, Porrello, ER. Evolution, comparative biology and ontogeny of vertebrate heart regeneration.. NPJ Regen Med 1: 16012 2016
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  • Morrison, JL, Zhang, S, Tellam, RL, Brooks, DA, McMillen, IC, Porrello, ER, Botting, KJ. Regulation of microRNA during cardiomyocyte maturation in sheep. BMC Genomics 16(1) : 541 2015
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  • Foster, SR, Porrello, ER, Stefani, M, Smith, NJ, Molenaar, P, dos Remedios, CG, Thomas, WG, Ramialison, M. Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation. Naunyn-Schmiedeberg's Archives of Pharmacology 388(10) : 1009 -1027 2015
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  • Sim, CB, Ziemann, M, Kaspi, A, Harikrishnan, KN, Ooi, J, Khurana, I, Chang, L, Hudson, JE, El‐Osta, A, Porrello, ER. Dynamic changes in the cardiac methylome during postnatal development. The FASEB Journal 29(4) : 1329 -1343 2015
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  • Voges, H, Mills, R, Porrello, E, Hudson, J. An in vitro model of acute myocardial damage in human bioengineered heart muscle. Heart Lung and Circulation 24: s196 2015
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