Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for...
Professor Porrello is the Theme Director of Stem Cell Biology and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute. He also directs the Melbourne Node of the recently established Novo Nordisk Foundation Centre for Stem Cell Medicine (reNEW) and he is the founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen). Prof Porrello’s research focuses on the development of regenerative therapies for children and adults with heart failure. Over the course of his career, he has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human organoids for drug discovery. Prof Porrello is a co-founder of Dynomics, a biotechnology company focused on the development of new heart failure treatments using organoid technologies.
After completing his PhD in Physiology at The University of Melbourne, Prof Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA. Upon returning to Australia in 2012, Prof Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017.
Top Publications
Lock, M, Tellam, R, Porrello, E, Soo, J, Darby, J, Brooks, D, Morrison, J.
miR-133a and Target Gene Expression in the Foetus and 6 Month Old Sheep Heart in Response to Myocardial Infarction.
Heart Lung and Circulation
25:
s117
2016
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Morrison, JL, Zhang, S, Tellam, RL, Brooks, DA, McMillen, IC, Porrello, ER, Botting, KJ.
Regulation of microRNA during cardiomyocyte maturation in sheep.
BMC Genomics
16(1)
:
541
2015
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Foster, SR, Porrello, ER, Stefani, M, Smith, NJ, Molenaar, P, dos Remedios, CG, Thomas, WG, Ramialison, M.
Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation.
Naunyn-Schmiedeberg's Archives of Pharmacology
388(10)
:
1009 -1027
2015
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Sim, CB, Ziemann, M, Kaspi, A, Harikrishnan, KN, Ooi, J, Khurana, I, Chang, L, Hudson, JE, El‐Osta, A, Porrello, ER.
Dynamic changes in the cardiac methylome during postnatal development.
The FASEB Journal
29(4)
:
1329 -1343
2015
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Voges, H, Mills, R, Porrello, E, Hudson, J.
An in vitro model of acute myocardial damage in human bioengineered heart muscle.
Heart Lung and Circulation
24:
s196
2015
view publication