photo of Prof David Elliott

Prof David Elliott

Prof David Elliott

Details

Role Group Leader / Principal Research Fellow
Research area Stem Cell Medicine

Contact

Available for student supervision
Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW). Prfoessor Elliott co-directs, with Associate Professor Rachel Conyers, the Australian Cardio-Oncology Registry (ACOR), a national program targeted at improving long-term cardiac health outcomes for childhood cancer survivors. The focus of Professor Elliott’s laboratory is to develop pluripotent stem cell-based models of heart disease and use these models to find new therapies for heart disease. Throughout his career Professor Elliott has made important contributions to understanding the molecular control of heart muscle development, function and disease.

Professor David Elliott completed his PhD on the genetics of heart development at The Victor Chang Cardiac Research Institute and The Walter and Eliza Hall Institute. He continued to post-doctoral studies at the University of Cambridge studying the nervous system in the fruit fly at the Wellcome Trust/Cancer Research UK Gurdon Institute. Professor Elliott began using human pluripotent stem cells in a second post-doc with Professors Andrew Elefanty and Ed Stanley at Monash University where he generated key stem cell lines and identified the first cardiac lineage cell surface markers.
Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW). Prfoessor Elliott co-directs, with...
Professor David Elliott leads the Heart Disease group at the Murdoch Children's Research Institute (MCRI) and he is a principal investigator of the Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW). Prfoessor Elliott co-directs, with Associate Professor Rachel Conyers, the Australian Cardio-Oncology Registry (ACOR), a national program targeted at improving long-term cardiac health outcomes for childhood cancer survivors. The focus of Professor Elliott’s laboratory is to develop pluripotent stem cell-based models of heart disease and use these models to find new therapies for heart disease. Throughout his career Professor Elliott has made important contributions to understanding the molecular control of heart muscle development, function and disease.

Professor David Elliott completed his PhD on the genetics of heart development at The Victor Chang Cardiac Research Institute and The Walter and Eliza Hall Institute. He continued to post-doctoral studies at the University of Cambridge studying the nervous system in the fruit fly at the Wellcome Trust/Cancer Research UK Gurdon Institute. Professor Elliott began using human pluripotent stem cells in a second post-doc with Professors Andrew Elefanty and Ed Stanley at Monash University where he generated key stem cell lines and identified the first cardiac lineage cell surface markers.

Top Publications

  • Low, YC, McKnight, CL, Elliott, DA, Thorburn, DR, Frazier, AE. Generation of a pluripotent embryonic stem cell TAFAZZIN hESC model (WAe009-A-3H) of Barth syndrome.. Stem Cell Res 93: 103948 2026
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  • Porrello, ER, Lee, CJM, Foo, RSY, Elliott, DA. Transcriptional regulation in heart development, disease and regeneration: reassessing the fetal gene hypothesis.. Nat Rev Cardiol 23(3) : 183 -196 2026
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  • Conyers, R, Stenta, T, Felmingham, B, Somogyi, A, Kirkpatrick, C, Halman, A, Moore, C, Khatri, D, Williams, E, Dyas, R, et al. Protocol for a prospective feasibility study investigating phenoconversion of CYP3A4, CYP2C19 and CYP2D6 genotypes in paediatric and adolescent and young adult patients with an acute diagnosis of Hodgkin or Non-Hodgkin Lymphoma [PEGASUS]. 2026
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  • Pocock, M, Reid, JD, Robinson, HR, Charitakis, N, Krycer, JR, Foster, SR, Fitzsimmons, RL, Lor, M, Tuano, N, Howden, S, et al. Maturation of human cardiac organoids enables complex disease modelling and drug discovery. 2026
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  • Hespe, S, Singer, ES, Reuter, C, Murray, B, Jordan, E, Chowns, J, Peters, S, Mayers, M, Gray, B, Hershberger, RE, et al. Clinical Validity of Autosomal Dominant ALPK3 Loss-of-function Variants as a Cause of Hypertrophic Cardiomyopathy. 2026
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