Antimicrobials, which include antibiotics, antivirals, antifungals and antiparasitic medications, are the most frequently prescribed medications in children.

Unfortunately, there is clear inequity in access to effective antimicrobial treatment in children compared with adults. This leads to worse clinical outcomes (morbidity) and death (mortality) from infection, with ineffective treatment also driving antibiotic resistance.

To tackle these issues, our antimicrobial research aims to facilitate interdisciplinary collaborations to:

  • Conduct rigorous clinical trials of therapeutics in children
  • Improve the safety, efficacy and accessibility of treatment using pharmacometrics
  • Utilise genomics and digital health to personalise medication use for children
  • Collect data on off-label medication use in children to inform future safer prescribing practices