Dr Kevin Watt
Dr Kevin Watt
Details
Role
Team Leader, Therapeutic Development
Research area
Stem Cell Medicine
Group
Heart Regeneration
Dr. Kevin Watt is a Team Leader in the Heart Regeneration and Disease Laboratories at Murdoch Children's Research Institute and an Associate Investigator at reNEW Melbourne Novo Nordisk Foundation Center for Stem Cell Medicine.
Our vision is to use human stem cell derived models to develop targeted therapies to treat heart failure in children. Our team are internationally recognised for our expertise using human pluripotent stem cells and animal models to study the fundamental mechanisms governing muscle development, maturation and regeneration. Building on our broad knowledge base, we seek to translate these fundamental discoveries towards new pharmacological and cell-based therapeutics to treat childhood cardiomyopathy and cardiotoxicity.
Dr. Watt obtained a PhD at the University of Aberdeen, UK (2010) and completed post-doctoral research positions at the Peter MacCallum Cancer Centre (2010), Baker Institute (2011-2018) and Centre of Muscle Research at The University of Melbourne (2018-2022). His work has been published in leading journals in the field including 2 x first author articles in Nature Communications and co-author publications in Nature, Cell Metab, Sci Transl Medicine, Circulation. Dr. Watt has served as a member of the council of the Australian Physiology Society (2021-2024).
Our vision is to use human stem cell derived models to develop targeted therapies to treat heart failure in children. Our team are internationally recognised for our expertise using human pluripotent stem cells and animal models to study the fundamental mechanisms governing muscle development, maturation and regeneration. Building on our broad knowledge base, we seek to translate these fundamental discoveries towards new pharmacological and cell-based therapeutics to treat childhood cardiomyopathy and cardiotoxicity.
Dr. Watt obtained a PhD at the University of Aberdeen, UK (2010) and completed post-doctoral research positions at the Peter MacCallum Cancer Centre (2010), Baker Institute (2011-2018) and Centre of Muscle Research at The University of Melbourne (2018-2022). His work has been published in leading journals in the field including 2 x first author articles in Nature Communications and co-author publications in Nature, Cell Metab, Sci Transl Medicine, Circulation. Dr. Watt has served as a member of the council of the Australian Physiology Society (2021-2024).
Dr. Kevin Watt is a Team Leader in the Heart Regeneration and Disease Laboratories at Murdoch Children's Research Institute and an Associate Investigator at reNEW Melbourne Novo Nordisk Foundation Center for Stem Cell Medicine.
Our vision is to...
Our vision is to...
Dr. Kevin Watt is a Team Leader in the Heart Regeneration and Disease Laboratories at Murdoch Children's Research Institute and an Associate Investigator at reNEW Melbourne Novo Nordisk Foundation Center for Stem Cell Medicine.
Our vision is to use human stem cell derived models to develop targeted therapies to treat heart failure in children. Our team are internationally recognised for our expertise using human pluripotent stem cells and animal models to study the fundamental mechanisms governing muscle development, maturation and regeneration. Building on our broad knowledge base, we seek to translate these fundamental discoveries towards new pharmacological and cell-based therapeutics to treat childhood cardiomyopathy and cardiotoxicity.
Dr. Watt obtained a PhD at the University of Aberdeen, UK (2010) and completed post-doctoral research positions at the Peter MacCallum Cancer Centre (2010), Baker Institute (2011-2018) and Centre of Muscle Research at The University of Melbourne (2018-2022). His work has been published in leading journals in the field including 2 x first author articles in Nature Communications and co-author publications in Nature, Cell Metab, Sci Transl Medicine, Circulation. Dr. Watt has served as a member of the council of the Australian Physiology Society (2021-2024).
Our vision is to use human stem cell derived models to develop targeted therapies to treat heart failure in children. Our team are internationally recognised for our expertise using human pluripotent stem cells and animal models to study the fundamental mechanisms governing muscle development, maturation and regeneration. Building on our broad knowledge base, we seek to translate these fundamental discoveries towards new pharmacological and cell-based therapeutics to treat childhood cardiomyopathy and cardiotoxicity.
Dr. Watt obtained a PhD at the University of Aberdeen, UK (2010) and completed post-doctoral research positions at the Peter MacCallum Cancer Centre (2010), Baker Institute (2011-2018) and Centre of Muscle Research at The University of Melbourne (2018-2022). His work has been published in leading journals in the field including 2 x first author articles in Nature Communications and co-author publications in Nature, Cell Metab, Sci Transl Medicine, Circulation. Dr. Watt has served as a member of the council of the Australian Physiology Society (2021-2024).
Top Publications
- McNamara, JW, Parker, BL, Voges, HK, Mehdiabadi, NR, Bolk, F, Ahmad, F, Chung, JD, Charitakis, N, Molendijk, J, Zech, ATL, et al. Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle. Nature Cardiovascular Research 2(2) : 159 -173 2023 view publication
- Sartori, R, Hagg, A, Zampieri, S, Armani, A, Winbanks, CE, Viana, LR, Haidar, M, Watt, KI, Qian, H, Pezzini, C, et al. Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia.. Sci Transl Med 13(605) : 2021 view publication
- Watt, KI, Henstridge, DC, Ziemann, M, Sim, CB, Montgomery, MK, Samocha-Bonet, D, Parker, BL, Dodd, GT, Bond, ST, Salmi, TM, et al. Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease.. Nat Commun 12(1) : 2887 2021 view publication
- Sim, CB, Phipson, B, Ziemann, M, Rafehi, H, Mills, RJ, Watt, KI, Abu-Bonsrah, KD, Kalathur, RKR, Voges, HK, Dinh, DT, et al. Sex-Specific Control of Human Heart Maturation by the Progesterone Receptor.. Circulation 143(16) : 1614 -1628 2021 view publication
- Findeisen, M, Allen, TL, Henstridge, DC, Kammoun, H, Brandon, AE, Baggio, LL, Watt, KI, Pal, M, Cron, L, Estevez, E, et al. Treatment of type 2 diabetes with the designer cytokine IC7Fc.. Nature 574(7776) : 63 -68 2019 view publication
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