A/Prof Silvia Velasco
A/Prof Silvia Velasco
Details
Role
Group Leader / Principal Research Fellow
Research area
Stem Cell Medicine
Group
Neural Stem Cells
Using pluripotent stem cell-derived 3D models of the human brain to study and identify new therapeutic approaches for neurological disorders.
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by using pluripotent stem-cell derived 3D brain organoids which reliably mimic processes of human brain development and disease in vitro.
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by using pluripotent stem-cell derived 3D brain organoids which reliably mimic processes of human brain development and disease in vitro.
Using pluripotent stem cell-derived 3D models of the human brain to study and identify new therapeutic approaches for neurological disorders.
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by...
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by...
Using pluripotent stem cell-derived 3D models of the human brain to study and identify new therapeutic approaches for neurological disorders.
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by using pluripotent stem-cell derived 3D brain organoids which reliably mimic processes of human brain development and disease in vitro.
Our lab is interested in understanding the cellular and molecular basis of human brain diseases by using pluripotent stem-cell derived 3D brain organoids which reliably mimic processes of human brain development and disease in vitro.
Top Publications
- Velasco, S, Kedaigle, AJ, Simmons, SK, Nash, A, Rocha, M, Quadrato, G, Paulsen, B, Nguyen, L, Adiconis, X, Regev, A, et al. Individual brain organoids reproducibly form cell diversity of the human cerebral cortex.. Nature 570(7762) : 523 -527 2019 view publication
- Velasco, S, Paulsen, B, Arlotta, P. Highly reproducible human brain organoids recapitulate cerebral cortex cellular diversity.. 2019 view publication
- Nucera, Charitakis, N, Leung, R, Leichter, A, Tuano, N, Walkiewicz, M, Sawant, V, Rowley, L, Scurr, M, Er, P, et al. Application of spatial transcriptomics across organoids: a high-resolution spatial whole-transcriptome benchmarking dataset. 2026 view publication
- Wang, C, Prawer, YDJ, Voogd, O, Schuster, J, Pasquali, C, De Paoli-Iseppi, R, Li, A, Hallab, J, Tian, L, Peng, H, et al. Igniting full-length isoform analysis in single-cell and spatial RNA-seq data with FLAMESv2. 2026 view publication
- Payne, JM, Haebich, KM, Mitchell, R, Bozaoglu, K, Giliberto, E, Lockhart, PJ, Maier, A, Velasco, S, Ball, G, North, KN, et al. Brain volumes in genetic syndromes associated with mTOR dysregulation: a systematic review and meta-analysis.. Mol Psychiatry 30(4) : 1676 -1688 2025 view publication
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