photo of Yau Low

Yau Low

Yau Low

Details

Role Research Officer
Research area Genomic Medicine

Top Publications

  • Low, YC, McKnight, CL, Stojanovski, D, Thorburn, DR, Frazier, AE. Generation of a pluripotent human AGK knockout embryonic stem cell model (WAe009-A-3C) of Sengers syndrome.. Stem Cell Res 90: 103895 2026
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  • Lewis, AC, Gruber, E, Franich, R, Armstrong, J, Kelly, MJ, Opazo, CM, Low, YC, Flippe, L, Wijanarko, K, Rowe, CL, et al. Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia.. Cell 189(1) : 215 -232.e24 2026
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  • Kugapreethan, R, Elahee Doomun, SN, Sacharz, J, Frazier, AE, Sharma, T, Low, YC, Nie, S, Leeming, MG, Muellner-Wong, L, Last, K, et al. Complex II assembly drives metabolic adaptation to OXPHOS dysfunction.. Sci Adv 11(33) : eadr6012 2025
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  • McKnight, CL, Low, YC, Elliott, DA, Thorburn, DR, Frazier, AE. Modelling Mitochondrial Disease in Human Pluripotent Stem Cells: What Have We Learned?. Int J Mol Sci 22(14) : 2021
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  • Jackson, TD, Hock, DH, Fujihara, KM, Palmer, CS, Frazier, AE, Low, YC, Kang, Y, Ang, C-S, Clemons, NJ, Thorburn, DR, et al. The TIM22 complex mediates the import of sideroflexins and is required for efficient mitochondrial one-carbon metabolism.. Mol Biol Cell 32(6) : 475 -491 2021
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