Dr Katherine Lee
Dr Katherine Lee has a Bachelor of Science in Mathematics from the University of Nottingham UK, a Masters of Science in Medical Statistics from the University of Leicester UK and a PhD in Biostatistics from the University of Cambridge.
She has over eight years experience in the design, planning and analysis of randomised trials and observational studies and is currently the responsible statistician for 10 clinical trials recruiting participants at The Royal Children's Hospital, including four multicentre and two international trials. She also has methodological interest in multiple imputation for dealing with missing data.
- Associate Director (Biostatistics), Melbourne Children's Trials Centre
- Honorary Fellow, Department of Paediatrics, University of Melbourne
- Poster Award – Eighth International Congress on Drug Therapy in HIV, 2006
- Student Conference Award – International Society for Clinical Biostatistics, 2005
- Scientific writing award – University of Cambridge, 2004
Dr Katherine Lee's main area of interest within the hospital is in the design and analysis of clinical trials. She is an active member of the team for a broad range of trials being carried out across the Melbourne Children's Campus. She also has a keen interest in preterm children, and in particular the longitudinal development of this at risk population.
Dr Lee also has a statistical research focus in the methods of multiple imputation for dealing with missing data. Her particular interest is in practical issues surrounding the implementation of this approach in the context of large longitudinal studies.
- Melbourne Children's Trials Centre
- Clinical Epidemiology and Biostatistics Unit
- Victorian Centre for Biostatistics (ViCBiostat)
- Victorian Infant Brain Studies (VIBeS)
- Rotavirus program
Lee KJ and Carlin JC. Multiple Imputation for Missing Data: Fully Conditional Specification versus Multivariate Normal. American Journal of Epidemiology 2010 Mar; 1;171(5):624-32
Spittle AJ, Anderson PJ, Lee KJ, Ferretti C, Eeles A, Orton J, Boyd RN, Inder T, Doyle LW. Preventive care at home for very preterm infants improves infant and caregiver outcomes at 2 years. Pediatrics. 2010 Jul;126(1):e171-8
Doyle LW, Cheong J, Hunt R, Lee K, Thompson D, Davis PG, Rees S, Anderson PJ, Inder TE. Caffeine and brain development in very preterm infants. Ann Neurol. 2010 Nov;68(5):734-42
Lee KJ and Carlin JB. Recovery of information from multiple imputation: a simulation study. Emerging Themes in Epidemiology. 2012 Jun 13;9(1):3
Cheong JLY, Coleman L, Hunt RW, Lee KJ, Doyle LW, Inder TE, and Jacobs SE. Prognostic utility of magnetic resonance imaging in neonatal hypoxic-ischemic encephalopathy: substudy of a randomized trial. Archives of Pediatrics & Adolescent Medicine. 2012 Jul 1;166(7):634-40
Spencer-Smith MM, Spittle AJ, Doyle LW, Lee KJ, Lorefice L, Suetin A, Pascoe L, Anderson PJ. Long-term benefits of home-based preventative care for preterm infants: outcomes from a randomized trial. Pediatrics. 2012 Dec; 130(6): 1094-101
Lee KJ, Galati JC, Simpson JA and Carlin JB. Comparison of methods for imputing ordinal variables using the multivariate normal model in multiple imputation. Stats in Medicine. 2012 Dec 30; 31(30):4164-74
Carlin JB, Macartney K, Lee KJ, Quinn H, Buttery J, McIntyre P, Bines J. Rotavirus vaccination and risk of intussusception: case-series and case-control analysis of confirmed cases in Australia. Clinical Infection Diseases. 2013 Nov; 57(10):1427-34
Lee KL and Simpson JA. Introduction to multiple imputation for dealing with missing data. Respirology. doi: 10.1111/resp.12226. [Epub ahead of print]
Lee KJ and Carlin JB. Fractional polynomial adjustment for time-varying covariates in a self-controlled case series analysis. Stats in Med. 2014 Jan 15; 33(1):105-16