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Professor Jane Halliday
Some of her key professional achievements include being President of the Australasian Epidemiological Association from 2004-8, giving the 2010 Human Genetics Society of Australasia Conference Oration – “in recognition of her outstanding contribution to human genetics in Australia”, and sitting on the Australian Health Ethics Committee and the NHMRC Human Genetics Advisory Committee for many years. Most recently, she was selected as one of the “Brilliant Minds” of the MCRI for the 30th anniversary celebrations in 2017.
- 2007: Fellowship of the Public Health Association of Australia (FPHAA)
- 2010: Orator for the Human Genetics Society of Australasia- presented with Certificate for 'Outstanding Contribution to Human Genetics in Australia'
Professor Halliday's current research focuses on uptake of new genetic technologies, particularly those related to prenatal diagnosis and population screening for birth defects. She also investigates perinatal, child and young adult health outcomes following exposures in pregnancy.
Specifically, Professor Halliday's research aims to provide evidence that may assist consumers and their health professionals to be aware of and reduce the possible risks to unborn children of such exposures. Pregnancy exposures of interest include those associated with assisted reproductive technologies (ART) and, more recently, teratogens such as alcohol. Professor Halliday is currently leading a four-year study entitled AQUA (Asking Questions about Alcohol in pregnancy), an NHMRC-funded research project. It is a longitudinal cohort study designed to collect detailed information about alcohol consumption by pregnant women using a questionnaire, following up children to two years of age. She is also leading the GaP study which is examining how much genomic information pregnant women and their partners want about their unborn baby. She recently led a publication of a world-first study of health and wellbeing outcomes for young adults, 18 years and older, who were conceived using ART.
- Asking Questions about Alcohol in pregnancy (AQUA) study
- Genomes and Pregnancy (GaP) study
- Prenatal diagnosis data collection
- Young adults conceived by assisted reproductive technology
Jane has over 210 peer-reviewed publications. The following ones have been selected to demonstrate her research experience and collaboration in the field of ART:
- Sharon Lewis, David Amor, Anne Glynn, Leeanda Wilton, Jane Halliday. Child health after preimplantation genetic diagnosis. Reprod BioMed Online; doi: 1016/j.rbmo.2020.11.014; vol 42, 3, 609-619 (2021)
- SR Catford, S Lewis, J Halliday, J Kennedy, MK O’Bryan, J McBain, DJ Amor, L Rombauts, R Saffery, RJ Hart and RI McLachlan. Health and fertility of ICSI-conceived young men: study protocol Hum Reprod Open; doi: 10.1093/hropen/hoaa042 (2020)
- J Halliday, S Lewis, J Kennedy, D Burgner, M Juonala, K Hammarberg, D Amor, L Doyle, R Saffery, S Ranganathan, L Welsh, M Cheung, J McBain, S Hearps, R McLachlan. Health of 22-35 year olds conceived by Assisted Reproductive Technology. Fert & Stert doi:org/10.1016/j.fertnstert.2019.03.001. (2019)
- B Novakovic, S Lewis, J Halliday, et al. Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood. Nature Communications; 10: 3922. doi.org/10.1038/s41467-019-11929-9 (2019)
- Markus Juonala, Sharon Lewis, Robert McLachlan, Karin Hammarberg, Joanne Kennedy, Richard Saffery, John McBain, Liam Welsh, Michael Cheung, Lex W Doyle, David J Amor, David P Burgner, Jane Halliday.American Heart Association ideal cardiovascular health score and subclinical atherosclerosis in 22–35 year-old adults conceived with and without in vitro fertilization. Hum Reprod, Dec (2019)
- Sarah Catford, Robert I. McLachlan, Moira K. O’Bryan and Jane L. Halliday. Long-term follow-up of ICSI-conceived offspring compared with spontaneously conceived offspring: A systematic review of health outcomes beyond the neonatal period. Andrology: doi 10.1111/andr.12526 (2018)
- Sharon Lewis, Joanne Kennedy; David Burgner; Robert McLachlan; Sarath Ranganathan; Karin Hammarberg; Richard Saffery; David J Amor; Michael M.H Cheung; Lex W Doyle; Markus Juonala; Susan Donath; John McBain; Jane Halliday. Clinical review of 24-35 year olds conceived with and without in vitro fertilization: CHART Study protocol. Reprod Health. doi: 10.1186/s12978-017-0377-3 (2017)
- David J Amor, Sharon Lewis, Joanne Kennedy, Emily Habgood, John McBain, Robert I McLachlan, Luk J Rombauts, Katrina Williams, Jane Halliday, Health outcomes of school aged children conceived using donor sperm. Reprod BioMed Online doi.org/10.1016/j.rbmo.2017.06.01 (2017)
- Jane Halliday, Cate Wilson, Karin Hammarberg, et al. Comparing indicators of health and development of singleton young adults conceived with and without ART. Fert & Stert, 101 (4):1055-1063 (2014)
- Halliday, J., Outcomes for offspring of men having ICSI for male factor infertility. Asian J Andrology, 14(1): 116-20 (2012)
Some recent publications demonstrating other research:
- L Downie, J Halliday, S Lewis, et al. Exome sequencing in newborns with congenital deafness as a model for genomic newborn screening: the Baby Beyond Hearing project. Gen Med doi.org/10.1038/s41436- 019-0745-1 (2020)
- L Hui, E Szepe, J Halliday, C Lewis. Maternity healthcare professionals’ views and experiences of fetal genomic uncertainty: a review. Prenat Diag. doi: 0.1002/pd.5673 (2020)
- S Gjorgioski, J Halliday, M Riley, D Amor, M Delatycki, A Bankier. Genetics and pediatric hospital admissions, 1985 to 2017. Gen Med doi:10.1038/s41436-020-0871-9. (2020)
- L Hui, A Poulton, E Kluckow, A Lindquist, et al, J Halliday. A minimum estimate of the prevalence of 22q11 deletion syndrome and other chromosome abnormalities in a combined prenatal and postnatal cohort. Hum Reprod doi:10.1093/humrep/dez286 (2020)
- Hui, L, Lindquist, A, Poulton, et al., Halliday, J. State-wide utilization and performance of traditional and cell-free DNA-based prenatal testing pathways: the Victorian Perinatal Record Linkage (PeRL) study. US Obst Gyn; doi: 10.1002/uog.21899. (2019)
- E Kluckow, J Halliday, A Poulton, A Lindquist, et al. Association between timing of diagnosis of trisomy 21, 18 and 13 and maternal socioeconomic status in Victoria, Australia: a population-based cohort study from 2015-16. Prenat Diag, Dec (2019).
- AJ Howard-Bath, A Poulton, J Halliday, L Hui. Population-based trends in the prenatal diagnosis of sex chromosome aneuploidy before and after non-invasive prenatal testing, Prenat Diag; doi: 10.1002/pd.5363 (2018)
- A Lee, E Muggli, J Halliday, et al What do pregnant women eat, and are they meeting the recommended dietary requirements for pregnancy? 67, 70-76 (2018)
- S Smith, A Cai, M Wong, M S Sousa, M Peate, A Welsh, B Meiser, R Kaur, J Halliday, et al. Improving women's knowledge about prenatal screening in the era of non-invasive prenatal testing for Down syndrome - development and acceptability of a low literacy decision aid. BMC Preg Childbirth, (2018)
- A Poulton, S Lewis, L Hui, J Halliday. Preimplantation and prenatal diagnosis for single gene disorders: a population-based study from 1977 to 2016. Prenat Diag: doi 10.1002/pd5352 (2018).
- Loke Y.J, Muggli E, Nguyen L, Ryan J, Saffery R, Elliott E.J, Halliday J. Craig J Time- and dose-dependent associations between prenatal alcohol exposure and placental global DNA methylatio Epigenomics. doi 10.2217/epi-2017-0147 (2018)
- E Lostchuck, A Poulton, J Halliday, L Hui. Population-based trends in ultrasound-indicated prenatal diagnosis from 1994 to 2016: Two decades of change. US Obst Gyn, doi: 10.1002/uog.19107 (2018)
- J Halliday, C Muller, T Charles, F Norris, J Kennedy et al. Offering pregnant women different levels of genetic information from prenatal chromosome microarray: a prospective study Eur J Hum Gen, doi:10.1038/s41431-017-0084-0 (2018).