Prof John Bateman
Prof John Bateman
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Available for student supervision
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research is aimed at understanding the molecular basis of these disorders to improve diagnosis and counselling, identify new therapeutic targets and test the effectiveness of new treatments to ultimately improve the quality of life for children with these debilitating conditions
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s...
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research is aimed at understanding the molecular basis of these disorders to improve diagnosis and counselling, identify new therapeutic targets and test the effectiveness of new treatments to ultimately improve the quality of life for children with these debilitating conditions
Top Publications
- Yammine, KM, Mirda Abularach, S, Xiong, M, Kim, S-Y, Bikovtseva, AA, Butty, VL, Schiavoni, RP, Bateman, JF, Lamandé, SR, Shoulders, MD. Failed cellular surveillance enables pathogenic matrix deposition in a COL2A1-related osteoarthritis.. J Biol Chem 301(8) : 110436 2025 view publication
- Yammine, KM, Abularach, SM, Xiong, M, Kim, S-Y, Bikovtseva, AA, Butty, VL, Schiavoni, RP, Bateman, JF, Lamandé, SR, Shoulders, MD. Failed Cellular Surveillance Enables Pathogenic Matrix Deposition in a COL2A1-Related Osteoarthritis.. 2025 view publication
- Yammine, KM, Abularach, SM, Xiong, M, Kim, S-Y, Bikovtseva, AA, Butty, VL, Schiavoni, RP, Bateman, JF, Lamandé, SR, Shoulders, MD. Failed Cellular Surveillance Enables Pathogenic Matrix Deposition in a COL2A1 -Related Osteoarthritis.. 2025 view publication
- Shu, CC, Zaki, S, Blaker, C, Smith, SM, Burkhardt, D, Kung, L, Rowley, L, Sampurno, L, Elefanty, AG, Bateman, JF, et al. 672 Human iPSC-derived superficial-zone, deep-zone or hybrid chondrocyte organoids for osteochondral defect repair – first in-vivo study in rat. Osteoarthritis and Cartilage 33: s463 -s464 2025 view publication
- Yammine, KM, Mirda Abularach, S, Kim, S-Y, Bikovtseva, AA, Lilianty, J, Butty, VL, Schiavoni, RP, Bateman, JF, Lamandé, SR, Shoulders, MD. ER procollagen storage defect without coupled unfolded protein response drives precocious arthritis.. Life Sci Alliance 7(9) : 2024 view publication
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