Dr Sebastian King
Mr Sebastian King is a paediatric surgeon with a subspecialty interest in colorectal conditions affecting neonates and children. He completed his PhD in 2008 with The University of Melbourne at The Royal Children's Hospital. His research focused upon the motility patterns of children affected by slow transit constipation. His PhD was supported by scholarships from the Royal Australasian College of Surgeons and the NHMRC.
Following completion of his paediatric surgical training at The Royal Children's Hospital, he underwent further colorectal and neonatal surgical training at Cincinnati Children's Hospital, USA and The Hospital for Sick Children, Toronto, Canada.
Mr King's clinical role at The Royal Children's Hospital is now focused upon children born with anorectal malformations or Hirschsprung disease, and those affected by chronic constipation or short bowel disease. His ongoing research focused is supported by his MCRI Career Development Award. He is the recent recipient of the Royal Australasian College of Surgeons Senior Lecturer Fellowship.
Surgeon, Department of Paediatric Surgery, The Royal Children's Hospital
Consultant, Department of Clinical Nutrition, The Royal Children's Hospital
Honorary Senior Lecturer, Department of Paediatrics, University of Melbourne
RACS Senior Lecturer Fellowship – 2015
Brian Smith Memorial Award (RACS) – 2014
RACS Congress (Best Laboratory Paper) – 2006
Sir Edward Hughes Memorial Clinical Research Prize – 2005
Victorian Paediatrics Society Award – 2004
Mr Sebastian King's research is focused upon children born with anorectal malformations or Hirschsprung disease. In particular, he is interested in the long-term outcomes for the affected children and the impact that poor intestinal motility has upon their quality of life.
The other key component of Mr King's research is chronic constipation in children. This work, both clinical and research, continues the projects that formed the key aspects of his PhD thesis.
Long-term outcomes in children born with anorectal malformations
Long-term outcomes in children born with Hirschsprung disease
Colonic motility patterns in children with chronic constipation
Oesophageal motility patterns in children with oesophageal atresia
Pathophysiology and clinical presentations of intussusception
1. Southwell BR, Koh TL, Wong SQ, King SK, Ong S-Y, Lee M, Farmer PJ, Peck CJ, Sutcliffe JR, Stanton MP, Keck J, Cook DJ, Chow CW, Hutson JM. Decrease in nerve fibre density in human sigmoid colon circular muscle occurs with growth but not aging. Neurogastroenterol Motil 2010;22(4):439-45
2. Sutcliffe JR, King SK, Hutson JM, Southwell BR. What's new in the radiology and pathology of motility disorders in children. Sem Ped Surg 2010;19(2):81-5
3. King SK, Beasley SW. Should we seek a fistula-in-ano when draining a perianal abscess? J Paediatr Child Health 2010;46:273-4
4. King SK, Sutcliffe JR, Ong S-Y, Lee M, Koh TL, Wong SQ, Farmer PJ, Peck CJ, Stanton MP, Keck J, Cook DJ, Chow CW, Hutson JM, Southwell BR. Substance P and vasoactive intestinal peptide are reduced in right transverse colon in paediatric slow transit constipation. Neurogastroenterol Motil 2010;22:883-e234
5. Yik YI, Farmer PJ, King SK , Chow CW, Hutson JM, Southwell BR. Gender differences in reduced substance P (SP) in children with slow-transit constipation. Pediatr Surg Int 2011;27:699-704.
6. Clarke MCC, Catto-Smith AC, King SK, Dinning PG, Cook IJ, Chase JW, Gibb SM, Robertson VJ, Simpson D, Hutson JM, Southwell BR. Transabdominal electrical stimulation increases colonic propagating pressure waves in paediatric slow transit constipation. J Pediatr Surg 2012;47(12):2279-84.
7. Savage J, Clarnette T, King SK . Toy magnet ingestion and small bowel obstruction: a lesson for both paediatricians and surgeons. J Paediatr Child Health 2013;49:E461-2.
8. Levitt MA, King SK, Bischoff A, Alam S, Gonzalez G, Pena A. The Gonzalez hernia revisited: use of the ischiorectal fat pad to aid in the repair of rectovaginal and rectourethral fistulae. J Pediatr Surg 2014;49(8):1308-10.
9. King SK, Cooksey R, Atkinson J, McLeod E, Levitt MA. Colonic perforation in a newborn with an anorectal malformation. ANZ J Surg 2014; DOI: 10.1111/ans.12704
Kodikara H, Efron D, Chow CW, MacGregor D, King SK. Infantile sigmoid colon stricture secondary to cytomegalovirus. ANZ J Surg 2014; DOI: 10.1111/ans.12921
MCRI – Career Development Award