Our first class facility provides stem cell derivation and gene-editing services to researchers worldwide.

About us

This facility brings together a team of highly experienced stem cell and molecular biologists with over 40 years of combined experience to generate standard and gene-edited iPSC lines in feeder-free and chemically defined medium in a manner that is both rapid and cost-effective.

A unique feature of our facility is the implementation of a streamlined one-step gene-editing/reprogramming protocol that utilises episomal reprogramming vectors and the Cas9/CRISPR gene-editing system to facilitate the rapid and efficient generation of clonally derived gene-edited iPSC lines from primary fibroblasts or blood.

We also have the capacity to perform gene-editing in already existing human pluripotent stem cell lines as well as the generation of lineage-specific reporter lines. 

Upon initial contact, we liaise with customers to devise the ideal strategy for achieving a successful gene-editing outcome based upon the ever-expanding number of gene-editing tools available including: 

  • SpCas9
  • Cas12
  • ABE and CBE Base Editing
  • Prime Editing

The iPSC Derivation & Gene Editing Facility also offers other key services such as MEF production, and customised training. 

Supported by

The iPSC Derivation & Gene Editing Facility was established using a generous donation from the Stafford Fox Medical Research Foundation. It is currently supported by Phenomics Australia (PA), and the Novo Nordisk Foundation reNEW Center for Stem Cell Medicine (NNF21CC0073729). PA is supported by the Australian Government through the National Collaborative Research Infrastructure Strategy (NCRIS) program.

Contact us and order enquiries

For more information and order enquiries, please contact us:

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