VITALITY Trial

Research area: Population Health > Population Allergy  | Status: Active

children eating

VITALITY aims to determine if vitamin D supplementation leads to a reduction in challenge-proven food allergy.

Recruitment for the Vitality study is now closed, with results from the study due throughout 2023.

There has been an increase in food allergy in recent years. The cause of this is unknown; however, the number of people experiencing allergic reactions has significantly increased. The aims of this study is to see the relationship between food allergy, vitamin D and immune function in infants.

Recruitment for the Vitality study is now closed, with results from the study due throughout 2023.

There has been an increase in food allergy in recent years. The cause of this is unknown; however, the number of people experiencing allergic reactions...

Recruitment for the Vitality study is now closed, with results from the study due throughout 2023.

There has been an increase in food allergy in recent years. The cause of this is unknown; however, the number of people experiencing allergic reactions has significantly increased. The aims of this study is to see the relationship between food allergy, vitamin D and immune function in infants.

Overview

To help understand more about Vitamin D and food allergy, more than 2,700 infants aged between six-to-12 weeks – who were predominantly breastfed and not taking Vitamin D were enrolled in the Trial. Each infant was given a vitamin drop every day and attended a free allergy test at 12 months of age.

What’s new?

Recruitment has closed and final data will be collected around April 2023, however, the team has already started analysing samples and surveys. Results are expected throughout 2023.

Six-year follow up

The Trial has begun a six-year follow-up to explore the effects of vitamin D on eczema, asthma and your child’s heart, hearing and developing teeth. VITALITY participants will be invited back into the clinic when they turn six for another free allergy test, as well as lung function, dental, hearing and cardiometabolic assessments. This will help expand our research beyond the food allergy status of children.

Who was enrolled?

Mothers with infants:

  • Age 6-12 weeks
  • Planning to be primarily breastfed until 6 months of age (not exclusively bottle-fed)
  • Living in Greater Melbourne, Victoria

What's involved?

  • Taking part in one initial home visit where samples were collected.
  • Completing four (4) online surveys in your child’s first year of life.
  • Attending a free allergy test appointment when your child turns one year old at the Royal Children’s Hospital.
  • Giving your baby one drop of a vitamin or placebo every day.
  • A six-year follow-up, including a free allergy test, lung function, dental, hearing and cardiometabolic assessments.

More resources


Contact us

VITALITY Study
Murdoch Children's Research Institute
The Royal Children's Hospital
50 Flemington Road
Parkville VIC 3052
Australia

Dr Jana Eckert
Phone: +61 3 9936 6027
Email:

 
 
child in hospital

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