photo of Dr Claudine Kraan

Dr Claudine Kraan

Dr Claudine Kraan

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Role Research Officer

Contact

Available for student supervision
Dr Kraan is a cognitive neuroscientist working in the Diagnosis and Development group at the Murdoch Children’s Research Institute (MCRI). She was awarded a PhD at Monash University in 2014 and is currently undertaking an NHMRC Peter Doherty fellowship in the Genomic Medicine research area at MCRI.

Dr Kraan has a strong interest in the genetic and epigenetic correlates of gait, motor control and cognitive phenotypes in individuals with neurogenetic conditions. She works closely with stakeholders and persons with lived experience of FMR1-related conditions linked to the fragile X premutation; and conditions associated with intellectual disability with a specific focus on fragile X syndrome, Angelman syndrome and Prader-Willi syndrome.

Dr Kraan is a member of the Department of Paediatrics Honours Committee, the Fragile X Association of Australia Scientific Committee and chair/organiser of the annual Fragile X syndrome Roundtable.

Dr Kraan has received highly esteemed awards in recognition of her work, including the Mollie Holman Award for best PhD in the Faculty of Medicine, Nursing and Health Sciences at Monash University, and the Graeme Clarke Health Tech Innovation Challenge prize at Graeme Clark Institute, Melbourne School of Engineering.
Dr Kraan is a cognitive neuroscientist working in the Diagnosis and Development group at the Murdoch Children’s Research Institute (MCRI). She was awarded a PhD at Monash University in 2014 and is currently undertaking an NHMRC Peter Doherty...
Dr Kraan is a cognitive neuroscientist working in the Diagnosis and Development group at the Murdoch Children’s Research Institute (MCRI). She was awarded a PhD at Monash University in 2014 and is currently undertaking an NHMRC Peter Doherty fellowship in the Genomic Medicine research area at MCRI.

Dr Kraan has a strong interest in the genetic and epigenetic correlates of gait, motor control and cognitive phenotypes in individuals with neurogenetic conditions. She works closely with stakeholders and persons with lived experience of FMR1-related conditions linked to the fragile X premutation; and conditions associated with intellectual disability with a specific focus on fragile X syndrome, Angelman syndrome and Prader-Willi syndrome.

Dr Kraan is a member of the Department of Paediatrics Honours Committee, the Fragile X Association of Australia Scientific Committee and chair/organiser of the annual Fragile X syndrome Roundtable.

Dr Kraan has received highly esteemed awards in recognition of her work, including the Mollie Holman Award for best PhD in the Faculty of Medicine, Nursing and Health Sciences at Monash University, and the Graeme Clarke Health Tech Innovation Challenge prize at Graeme Clark Institute, Melbourne School of Engineering.

Top Publications

  • Kraan, CM, Cornish, KM, Bui, QM, Li, X, Slater, HR, Godler, DE. β-glucuronidase use as a single internal control gene may confound analysis in FMR1 mRNA toxicity studies. PLOS ONE 13(2) : e0192151 2024
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  • Kraan, CM, Cornish, KM, Bui, QM, Li, X, Slater, HR, Godler, DE. β-glucuronidase mRNA levels are correlated with gait and working memory in premutation females: understanding the role of FMR1 premutation alleles. Scientific Reports 6(1) : 29366 2024
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  • Baker, EK, Arpone, M, Kraan, C, Bui, M, Rogers, C, Field, M, Bretherton, L, Ling, L, Ure, A, Cohen, J, et al. FMR1 mRNA from full mutation alleles is associated with ABC-CFX scores in males with fragile X syndrome. Scientific Reports 10(1) : 11701 2024
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  • Kraan, CM, Baker, EK, Arpone, M, Bui, M, Ling, L, Gamage, D, Bretherton, L, Rogers, C, Field, MJ, Wotton, TL, et al. DNA Methylation at Birth Predicts Intellectual Functioning and Autism Features in Children with Fragile X Syndrome. International Journal of Molecular Sciences 21(20) : 7735 2024
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  • Baker, EK, Arpone, M, Bui, M, Kraan, CM, Ling, L, Francis, D, Hunter, MF, Rogers, C, Field, MJ, Santa María, L, et al. Tissue mosaicism, FMR1 expression and intellectual functioning in males with fragile X syndrome. American Journal of Medical Genetics Part A 191(2) : 357 -369 2023
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